Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma (Homo sapiens)

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FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma
Evading growth suppressors

G1 to S cell cycle control (Homo sapiens)

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G1 to S cell cycle control
Activating invasion and metastasis

Neural crest cell migration in cancer (Homo sapiens)

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Neural crest cell migration in cancer
Enabling replicative immortality

Wnt signaling, NetPath (Homo sapiens)

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Wnt signaling, NetPath
Inducing angiogenesis

VEGFA-VEGFR2 signaling (Homo sapiens)

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VEGFA-VEGFR2 signaling
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

TCA cycle nutrient use and invasiveness of ovarian cancer (Homo sapiens)

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TCA cycle nutrient use and invasiveness of ovarian cancer
Genome instability and mutation

Base excision repair (Homo sapiens)

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Base excision repair
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment
Therapeutics

Cancer immunotherapy by CTLA4 blockade (Homo sapiens)

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Cancer immunotherapy by CTLA4 blockade
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