Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Translation inhibitors in chronically activated PDGFRA cells (Homo sapiens)

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Translation inhibitors in chronically activated PDGFRA cells
Evading growth suppressors

TGF-beta receptor signaling (Homo sapiens)

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TGF-beta receptor signaling
Activating invasion and metastasis

MFAP5-mediated ovarian cancer cell motility and invasiveness (Homo sapiens)

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MFAP5-mediated ovarian cancer cell motility and invasiveness
Enabling replicative immortality

Regulation of Wnt / B-catenin signaling by small molecule compounds (Homo sapiens)

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Regulation of Wnt / B-catenin signaling by small molecule compounds
Inducing angiogenesis

Hedgehog signaling (Homo sapiens)

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Hedgehog signaling
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

Fatty acid beta-oxidation (Homo sapiens)

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Fatty acid beta-oxidation
Genome instability and mutation

DNA IR-double strand breaks and cellular response via ATM (Homo sapiens)

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DNA IR-double strand breaks and cellular response via ATM
Tumor promoting inflammation

Chemokine signaling (Homo sapiens)

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Chemokine signaling
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
Therapeutics

Irinotecan pathway (Homo sapiens)

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Irinotecan pathway
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