Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

ErbB signaling (Homo sapiens)

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ErbB signaling
Evading growth suppressors

TGF-beta receptor signaling (Homo sapiens)

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TGF-beta receptor signaling
Activating invasion and metastasis

Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens)

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Epithelial to mesenchymal transition in colorectal cancer
Enabling replicative immortality

Wnt signaling, NetPath (Homo sapiens)

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Wnt signaling, NetPath
Inducing angiogenesis

PDGF pathway (Homo sapiens)

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PDGF pathway
Resisting cell death

miRNA regulation of p53 pathway in prostate cancer (Homo sapiens)

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miRNA regulation of p53 pathway in prostate cancer
Deregulating cellular energetics

Fatty acid beta-oxidation (Homo sapiens)

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Fatty acid beta-oxidation
Genome instability and mutation

DNA IR-double strand breaks and cellular response via ATM (Homo sapiens)

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DNA IR-double strand breaks and cellular response via ATM
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment
Therapeutics

Photodynamic therapy-induced HIF-1 survival signaling (Homo sapiens)

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Photodynamic therapy-induced HIF-1 survival signaling
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