Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Hippo-Merlin signaling dysregulation (Homo sapiens)

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Hippo-Merlin signaling dysregulation
Evading growth suppressors

Tumor suppressor activity of SMARCB1 (Homo sapiens)

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Tumor suppressor activity of SMARCB1
Activating invasion and metastasis

Focal adhesion: PI3K-Akt-mTOR-signaling (Homo sapiens)

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Focal adhesion: PI3K-Akt-mTOR-signaling
Enabling replicative immortality

ncRNAs involved in STAT3 signaling in hepatocellular carcinoma (Homo sapiens)

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ncRNAs involved in STAT3 signaling in hepatocellular carcinoma
Inducing angiogenesis

Hedgehog signaling (Homo sapiens)

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Hedgehog signaling
Resisting cell death

Apoptosis (Homo sapiens)

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Apoptosis
Deregulating cellular energetics

TCA cycle nutrient use and invasiveness of ovarian cancer (Homo sapiens)

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TCA cycle nutrient use and invasiveness of ovarian cancer
Genome instability and mutation

ATR signaling (Homo sapiens)

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ATR signaling
Tumor promoting inflammation

Chemokine signaling (Homo sapiens)

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Chemokine signaling
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment
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