Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

PDGFR-beta pathway (Homo sapiens)

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PDGFR-beta pathway
Evading growth suppressors

TGF-beta signaling (Homo sapiens)

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TGF-beta signaling
Activating invasion and metastasis

Epithelial to mesenchymal transition in colorectal cancer (Homo sapiens)

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Epithelial to mesenchymal transition in colorectal cancer
Enabling replicative immortality

Notch signaling (Homo sapiens)

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Notch signaling
Inducing angiogenesis

VEGFA-VEGFR2 signaling (Homo sapiens)

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VEGFA-VEGFR2 signaling
Resisting cell death

miRNA regulation of p53 pathway in prostate cancer (Homo sapiens)

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miRNA regulation of p53 pathway in prostate cancer
Deregulating cellular energetics

TCA cycle nutrient use and invasiveness of ovarian cancer (Homo sapiens)

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TCA cycle nutrient use and invasiveness of ovarian cancer
Genome instability and mutation

DNA IR-damage and cellular response via ATR (Homo sapiens)

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DNA IR-damage and cellular response via ATR
Tumor promoting inflammation

IL1 signaling (Homo sapiens)

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IL1 signaling
Avoiding immune destruction

Altered glycosylation of MUC1 in tumor microenvironment (Homo sapiens)

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Altered glycosylation of MUC1 in tumor microenvironment