Flavonoid pathway (Arabidopsis thaliana)

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2Quercetin 3-rutinoside-7-rhamnoside7,4'-Dihydroxy-6-methoxyisoflavone, GlyciteinCatalystLuteolin 7-glucosideCyanidin 3-(6-p-coumaroylglucoside)Quercetin 3-neohesperidosideCyanidin 3-O-[2''-O-(xylosyl) glucoside] 5-O-(6'''-O-malonyl) glucosideCatalystCatalystGenkwaninCatalyst5,7-DimethoxyapigeninCatalystProductScutellarein 7-glucuronide7-Hydroxy-3',4'-dimethoxyflavoneCosmosiinRutin,Birutan6-HydroxluteolinCatalystepicatechin heptamerIsorhamnetin 3-rhamnoside-7-glucosideBiochanin ACyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-glucosideCatalyst7,3'-Dihydroxy-4'-methoxyflavone[Epicatechin-(4beta->8)]4-epicatechinDihydrokaempferolLuteolin 3',7-diglucosideCyanidin 3-(6-p-coumaroylglucoside)-5-glucosideCatalystFormononetin 7-GlucosideHesperidinCyanidin 3-(6-p-coumaroylsambubioside)FormononetinBiochanin A 7-glucosidedihydroquercetin, TaxifolinApigenin 7-rutinosideCinnamtannin A1CatalystCyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-glucosideProcyanidin C1MedicarpinCatalystNaringeninCatalystRXN-527Cyanidin 3-sophoroside7,4'-Dihydroxy-3'-methoxyflavoneDaidzein 7-glucosideIsorhamnetin 3-arabinosideLuteolin 5,7-diglucosideDiosmetin 7-rutinosideQuercetin 3-Arabinoside-7-rhamnosideHesperetinIsorhamnetinCyanidine 3-sambubiosideQuercetin 3,7-diglucosideCatalystQuercetin 3-O-alpha-L-arabinopyranosideGenistinGenistein2',4',5,7-Tetrahydroxy- isoflavanoneCyanidin 3-O-[2-O-(2-O-(sinapoyl)-bata-D-xylopyranosyl) 6-O-(4-O-(beta-D-glucopyranosyl)-p-coumaroyl-bata-D-glucopyranoside] 5-O-[6-O-(malonyl) bata-D-glucopyranoside]CatalystCatalystRXN-7775Isorhamnetin 3-neohesperidoside-7-rhamnosidePuerarin7,4'-Dihydroxyflavone2'-HydroxyformononetinIsorhamnetin 3-O-rutinosideHesperetin 7-glucosideCyanidin 3-O-[2''-O-(xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-[6'''-O-(malonyl) glucoside]Isorhamnetin 3-alpha-L-arabinopyranoside-7-rhamnosideHesperetin 7-neohesperidosidecatechin6-MethoxyluteolinRXN-525HomoeriodictyolIsorhamnetin 3-O-beta-glucopyranoside-7-O-alpha-rhamnopyranosideCatalystCyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) glucoside] 5-O-glucosideCatalystCatalystQuercetin 3-rhamnoside-7-glucosideProcyanidin B2VestitoneCatalyst6,7,4'-TrihydroxyflavanoneCyanidin 3,5-di-O-glucosideEriodictyolPrunetinCatalystCyanidin 3-(6-p-coumaroylglucoside)-5-(6-malonylglucoside)(+)-epicatechinLiquiritinApigenin 7,4'-dimethyl etherCatalystCyanidin 3-sambubioside-5-glucosideLiquilitigenin4'-MethylluteolinCyanidin 3-(6''-p-coumaryl-2'''-sinapylsambubioside)-5-(6-malonylglucoside)Isorhamnetin 3-neohesperidosideNaringenin 4'- O-glucoside7,3',4'-TrihydroxyflavoneRXN-1484LuteolinDaidzein2,6,7,4'-TetrahydroxyisoflavanoneIsorhamnetin 3-rhamnosidep-Coumaroyl-CoACyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucosideScutellarein8C-Glucosyl-2,7,4'- trihydroxyisoflavanonePruninCatalystIsorhamnetin 3,7-dirhamnoside7,2'-Dihydroxy-4'-methoxy-isoflavanolQuercetin 3-O-glucoside-7-O-rhamnosideCyanidin 3-(6''-(E)-p-coumarylsambubioside)-5-glucosideQuercetin 3-neohesperidoside-7-rhamnosideHirsutrin, Quercetin 3-GlucosideRXN-76522,7,4'-Trihydroxyiso- flavanoneLuteolin 4',7-diglucosideQuercetin 7-glucosideLeucocyanidinEpicatechin-(4beta->8)5-epicatechinDiosmetin 7-neohesperidosideCyanidin 3-glucosideCatalystIsoliquilitigeninApigeninCyanidinLuteolin 4'-glucosideAcacetinNARINGENIN-3- DIOXYGENASE-RXNIsorhamnetin 3-O-beta-D-glucopyranosideCatalystNaringinDiosmetin 7-glucosideCyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-glucoside3-O-MethylquercetinCatalyst6-HydroxydaidzeinNaringenin chalcone


Description

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Ontology Terms

 

Bibliography

  1. Saito K, Yonekura-Sakakibara K, Nakabayashi R, Higashi Y, Yamazaki M, Tohge T, Fernie AR; ''The flavonoid biosynthetic pathway in Arabidopsis: structural and genetic diversity.''; Plant Physiol Biochem, 2013 PubMed Europe PMC Scholia
  2. Brazier-Hicks M, Evans KM, Gershater MC, Puschmann H, Steel PG, Edwards R; ''The C-glycosylation of flavonoids in cereals.''; J Biol Chem, 2009 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
141092view06:39, 3 November 2025EgonwLonger description
118336view13:14, 27 May 2021Mkutmonpublication ref
103424view11:59, 28 February 2019DeSlVertical allignment, moved reactions closer together for readability.
103423view11:46, 28 February 2019DeSlHorizontal layout
103422view11:34, 28 February 2019DeSlUpdated layout left hand side
103421view10:02, 28 February 2019DeSlChanged layout (righthand side and middle).
103027view08:25, 1 February 2019TokimatsuFix Annotations.
103026view07:31, 1 February 2019TokimatsuFix interactions, topology and labels.
102670view01:37, 17 January 2019TokimatsuFix interactions and labels.
102669view01:20, 17 January 2019TokimatsuFix interactions.
102644view08:49, 16 January 2019Tokimatsuremove reactions/metabolites undiscovered from Brassicaceae. Add reaction IDs.
102628view07:23, 15 January 2019Tokimatsuremove reactions/metabolites undiscovered from Brassicaceae
101938view04:31, 19 November 2018EgonwRemoved "undefined" as data source.
96270view07:16, 3 March 2018EgonwFixed the syntax of a KNApSAcK ID (too many zeros).
95486view10:25, 18 December 2017DeSlChanged all arrows to MIM-type conversion.
95484view10:01, 18 December 2017DeSlConnected unconnected line
95445view07:27, 15 December 2017Kozo2add rhea annotation
92987view18:09, 21 July 2017Khanspersconnected interaction
92901view09:46, 15 July 2017EgonwModified description
87496view01:43, 25 July 2016AlexanderPicoOntology Term : 'classic metabolic pathway' added !
87495view01:43, 25 July 2016AlexanderPicoOntology Term : 'flavonoid biosynthetic pathway' added !
87428view12:10, 22 July 2016Kozo2replace Kaempferol ID from KNApSAcK to PubChem-compound
87330view11:42, 21 July 2016Kozo2test direct xml editing
87319view00:24, 21 July 2016AlexanderPicoupdated ID for Cyanidin
87251view10:45, 20 July 2016Kozo2Quick edit to datanode annotation or property
86212view18:16, 6 July 2016Kozo2Quick edit to datanode annotation or property
86211view17:44, 6 July 2016Kozo2Quick edit to datanode annotation or property
86210view17:34, 6 July 2016Kozo2Quick edit to datanode annotation or property
86007view07:57, 24 June 2016Kozo2Quick edit to datanode annotation or property
84960view19:00, 3 April 2016Kozo2confirm the feasibility of updating ID mappings from local pathvisio bridge
84959view17:46, 3 April 2016Kozo2replace non-KNApSAcK IDs to KNApSAcK
84958view16:42, 3 April 2016Kozo2replace non-KNApSAcK IDs to KNApSAcK
84957view15:55, 3 April 2016Kozo2assign KNApSAcK IDs to Apigenin derivative
84956view15:27, 3 April 2016Kozo2assign KNApSAcK IDs to Liquiritigenin derivative
84955view13:44, 3 April 2016Kozo2assign KNApSAcK IDs to Genistein derivative
84954view13:04, 3 April 2016Kozo2assign KNApSAcK IDs to Eriodictyol derivative
84953view11:08, 3 April 2016Kozo2assign KNApSAcK IDs to Luteolin derivative
84950view05:24, 3 April 2016Kozo2assign KNApSAcK IDs to Cyanidine derivative
84947view17:11, 2 April 2016Kozo2assign KNApSAcK IDs to Isorhamnetin derivative
84944view04:30, 2 April 2016Kozo2assign KNApSAcK IDs to Quercetin derivative
84943view03:55, 2 April 2016Kozo2assign KNApSAcK IDs to Kaempferol derivative
84942view03:38, 2 April 2016Kozo2assign KNApSAcK IDs to Kaempferol derivative
84890view01:48, 31 March 2016Kozo2assign KNApSAcK IDs to the compounds under Isoliquiritigenin
84889view23:50, 30 March 2016Kozo2Quick edit to datanode annotation or property
84888view23:49, 30 March 2016Kozo2assign KNApSAcK IDs to catechins
84872view08:34, 29 March 2016Kozo2Test updating KNApSAcK ID from PathVisio
84831view14:12, 24 March 2016Kozo2Quick edit to datanode annotation or property
84830view13:28, 24 March 2016Kozo2Quick edit to datanode annotation or property
84829view12:49, 24 March 2016Kozo2Quick edit to datanode annotation or property
84827view10:16, 24 March 2016Kozo2Quick edit to datanode annotation or property

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(+)-epicatechinMetabolite
2',4',5,7-Tetrahydroxy- isoflavanoneMetabolite102056-04-2 (CAS)
2'-HydroxyformononetinMetabolite
2,6,7,4'-TetrahydroxyisoflavanoneMetabolite
2,7,4'-Trihydroxyiso- flavanoneMetaboliteC15567 (KEGG Compound)
2-HydroxynaringeninMetabolite58124-18-8 (CAS)
3-O-MethylquercetinMetabolite
4'-MethylluteolinMetabolite
5,7-DimethoxyapigeninMetabolite
6,7,4'-TrihydroxyflavanoneMetabolite
6-HydroxluteolinMetabolite
6-HydroxydaidzeinMetabolite
6-MethoxyluteolinMetabolite
6C-Glucosyl-2- hydroxynaringeninMetabolite90657396 (PubChem-compound)
7,2'-Dihydroxy-4'-methoxy-isoflavanolMetabolite
7,3',4'-TrihydroxyflavoneMetabolite
7,3'-Dihydroxy-4'-methoxyflavoneMetabolite
7,4'-Dihydroxy-3'-methoxyflavoneMetabolite
7,4'-Dihydroxy-6-methoxyisoflavone, GlyciteinMetabolite
7,4'-DihydroxyflavoneMetaboliteC12123 (KEGG Compound)
7-Hydroxy-3',4'-dimethoxyflavoneMetabolite
8C-Glucosyl-2,7,4'- trihydroxyisoflavanoneMetabolite
AcacetinMetabolite
AfzelechinMetabolite2545-00-8 (CAS)
AfzelinMetabolite
Apigenin 7,4'-dimethyl etherMetabolite
Apigenin 7-rutinosideMetabolite
ApigeninMetabolite520-36-5 (CAS)
AstragalinMetabolite
Biochanin AMetabolite
Biochanin A 7-glucosideMetabolite
CatalystGeneProduct
CatalystPathwayR02442 (SWISS-MODEL)
CatalystPathwayR06556 (SWISS-MODEL)
CatalystPathwayR06793 (SWISS-MODEL)
CatalystPathwayR07317 (SWISS-MODEL)
CatalystGeneProduct
Cinnamtannin A1Metabolite
CosmosiinMetabolite
Cyanidin 3,5-di-O-glucosideMetabolite
Cyanidin 3-(6''-(E)-p-coumarylsambubioside)-5-glucosideMetabolite
Cyanidin 3-(6''-p-coumaryl-2'''-sinapylsambubioside)-5-(6-malonylglucoside)Metabolite
Cyanidin 3-(6-p-coumaroylglucoside)Metabolite
Cyanidin 3-(6-p-coumaroylglucoside)-5-(6-malonylglucoside)Metabolite
Cyanidin 3-(6-p-coumaroylglucoside)-5-glucosideMetabolite
Cyanidin 3-(6-p-coumaroylsambubioside)Metabolite
Cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(xylosyl) 6''-O-(p-O-(glucosyl) p-coumaroyl) glucoside] 5-O-[6'''-O-(malonyl) glucoside]Metabolite
Cyanidin 3-O-[2''-O-(xylosyl) glucoside] 5-O-(6'''-O-malonyl) glucosideMetabolite
Cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-glucosideMetabolite
Cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucosideMetabolite
Cyanidin 3-O-[2-O-(2-O-(sinapoyl)-bata-D-xylopyranosyl) 6-O-(4-O-(beta-D-glucopyranosyl)-p-coumaroyl-bata-D-glucopyranoside] 5-O-[6-O-(malonyl) bata-D-glucopyranoside]Metabolite
Cyanidin 3-glucosideMetabolite
Cyanidin 3-sambubioside-5-glucosideMetabolite
Cyanidin 3-sophorosideMetabolite
Cyanidine 3-sambubiosideMetabolite
CyanidinMetaboliteundefined (undefined)
DIHYDROKAEMPFEROL- 4-REDUCTASE-RXNDIHYDROKAEMPFEROL-4-REDUCTASE-RXN (HGNC)
Daidzein 7-glucosideMetabolite
DaidzeinMetaboliteC10208 (KEGG Compound)
DihydrokaempferolMetaboliteC00974 (KEGG Compound)
Diosmetin 7-glucosideMetabolite
Diosmetin 7-neohesperidosideMetabolite
Diosmetin 7-rutinosideMetabolite
EpiafzelechinMetaboliteundefined (undefined)
Epicatechin-(4beta->8)5-epicatechinMetabolite
EriodictyolMetabolite552-58-9 (CAS)
FormononetinMetabolite
Formononetin 7-GlucosideMetabolite
GenisteinMetaboliteC06563 (KEGG Compound)
GenistinMetabolite
GenkwaninMetabolite
HesperetinMetabolite
Hesperetin 7-glucosideMetabolite
Hesperetin 7-neohesperidosideMetabolite
HesperidinMetabolite
Hirsutrin, Quercetin 3-GlucosideMetabolite
HomoeriodictyolMetabolite
IsoliquilitigeninMetaboliteC08650 (KEGG Compound)
IsorhamnetinMetabolite
Isorhamnetin 3,7-dirhamnosideMetabolite
Isorhamnetin 3-O-beta-D-glucopyranosideMetabolite
Isorhamnetin 3-O-beta-glucopyranoside-7-O-alpha-rhamnopyranosideMetabolite
Isorhamnetin 3-O-rutinosideMetabolite
Isorhamnetin 3-alpha-L-arabinopyranoside-7-rhamnosideMetabolite
Isorhamnetin 3-arabinosideMetabolite
Isorhamnetin 3-neohesperidosideMetabolite
Isorhamnetin 3-neohesperidoside-7-rhamnosideMetabolite
Isorhamnetin 3-rhamnosideMetabolite
Isorhamnetin 3-rhamnoside-7-glucosideMetabolite
IsovitexinMetaboliteundefined (undefined)
Kaempferol 3,7-di-O-rhamnosideMetabolite
Kaempferol 3,7-diglucosideMetabolite
Kaempferol 3-O-rhamninosideMetabolite
Kaempferol 3-O-rutinosideMetabolite
Kaempferol 3-alpha-L-arabinofuranoside-7-rhamnosideMetabolite
Kaempferol 3-arabinosideMetabolite
Kaempferol 3-galactosideMetabolite
Kaempferol 3-galactoside-7-rhamnosideMetabolite
Kaempferol 3-gentiobiosideMetabolite
Kaempferol 3-glucoside-(1->6)-glucoside-7-alpha-L-rhamnosideMetabolite
Kaempferol 3-glucoside-7-rhamnosideMetabolite
Kaempferol 3-neohesperidosideMetabolite
Kaempferol 3-neohesperidoside-7-rhamnosideMetabolite
Kaempferol 3-rhamnoside-7-glucosideMetabolite
Kaempferol 3-robinoside (K 3-(6''-RhaGal))Metabolite
Kaempferol 7-neohesperidosideMetabolite
KaempferolMetaboliteundefined (undefined)
LEUCOPEL-RXNLEUCOPEL-RXN (HGNC)
LeucocyanidinMetabolite
LeucopelargonidinMetabolite520-17-2 (CAS)
LiquilitigeninMetaboliteundefined (undefined)
LiquiritinMetabolite
Luteolin 3',7-diglucosideMetabolite
Luteolin 4',7-diglucosideMetabolite
Luteolin 4'-glucosideMetabolite
Luteolin 5,7-diglucosideMetabolite
Luteolin 7-glucosideMetabolite
LuteolinMetaboliteC01514 (KEGG Compound)
MedicarpinMetabolite
NARINGENIN-3- DIOXYGENASE-RXNNARINGENIN-3-DIOXYGENASE-RXN (HGNC)
Naringenin 4'- O-glucosideMetabolite81202-36-0 (CAS)
Naringenin chalconeMetaboliteundefined (undefined)
NaringeninMetaboliteC00509 (KEGG Compound)
NaringinMetabolite
PelargonidinMetaboliteC05904 (KEGG Compound)
PopulninMetabolite
Procyanidin B2Metabolite
Procyanidin C1MetaboliteC17624 (KEGG Compound)
ProductScutellarein 7-glucuronideMetabolite
PrunetinMetaboliteundefined (SWISS-MODEL)
PruninMetabolite
PuerarinMetaboliteC10524 (KEGG Compound)
QuercetinMetabolite
Quercetin 3,7-diglucosideMetabolite
Quercetin 3,7-dirhamnosideMetabolite
Quercetin 3-Arabinoside-7-rhamnosideMetabolite
Quercetin 3-O-L-rhamnosideMetabolite
Quercetin 3-O-alpha-L-arabinopyranosideMetabolite
Quercetin 3-O-glucoside-7-O-rhamnosideMetabolite
Quercetin 3-neohesperidosideMetabolite
Quercetin 3-neohesperidoside-7-rhamnosideMetabolite
Quercetin 3-rhamnoside-7-glucosideMetabolite
Quercetin 3-rutinoside-7-rhamnosideMetabolite
Quercetin 7-glucosideMetabolite
RXN-1481RXN-1481 (STRING)
RXN-1484RXN-1484 (STRING)
RXN-525RXN-525 (HGNC)
RXN-527RXN-527 (HGNC)
RXN-7652RXN-7652 (STRING)
RXN-7775RXN-7775 (STRING)
RXN-9724RXN-9724 (STRING)
Rutin,BirutanMetabolite
SaponarinMetaboliteC08064 (KEGG Compound)
ScutellareinMetaboliteC10184 (KEGG Compound)
TilirosideMetabolite
VestitoneMetaboliteundefined (undefined)
[Epicatechin-(4beta->8)]4-epicatechinMetabolite
catechinMetaboliteC06562 (KEGG Compound)
dihydroquercetin, TaxifolinMetaboliteC01617 (KEGG Compound)
epicatechin heptamerMetabolite
p-Coumaroyl-CoAMetaboliteundefined (undefined)

Annotated Interactions

SourceTargetTypeDatabase referenceComment
6C-Glucosyl-2- hydroxynaringeninIsovitexinArrowRXN-14076 (BioCyc)
NaringeninNaringenin 4'- O-glucosideArrowR08006 (KEGG Reaction)
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