Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Hippo-Merlin signaling dysregulation (Homo sapiens)

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Hippo-Merlin signaling dysregulation
Evading growth suppressors

TGF-beta receptor signaling (Homo sapiens)

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TGF-beta receptor signaling
Activating invasion and metastasis

H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer (Homo sapiens)

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H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer
Enabling replicative immortality

Notch signaling (Homo sapiens)

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Notch signaling
Inducing angiogenesis

Angiogenesis (Homo sapiens)

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Angiogenesis
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

Fatty acid beta-oxidation (Homo sapiens)

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Fatty acid beta-oxidation
Genome instability and mutation

Regulation of sister chromatid separation at the metaphase-anaphase transition (Homo sapiens)

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Regulation of sister chromatid separation at the metaphase-anaphase transition
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
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