Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

MAPK signaling (Homo sapiens)

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MAPK signaling
Evading growth suppressors

Tumor suppressor activity of SMARCB1 (Homo sapiens)

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Tumor suppressor activity of SMARCB1
Activating invasion and metastasis

TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (Homo sapiens)

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TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition
Enabling replicative immortality

Notch signaling (Homo sapiens)

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Notch signaling
Inducing angiogenesis

Angiogenesis (Homo sapiens)

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Angiogenesis
Resisting cell death

PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer (Homo sapiens)

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PI3K-AKT-mTOR signaling and therapeutic opportunities in prostate cancer
Deregulating cellular energetics

Glycolysis and gluconeogenesis (Homo sapiens)

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Glycolysis and gluconeogenesis
Genome instability and mutation

Nucleotide excision repair (Homo sapiens)

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Nucleotide excision repair
Tumor promoting inflammation

IL1 signaling (Homo sapiens)

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IL1 signaling
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
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