Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Hepatocyte growth factor receptor signaling (Homo sapiens)

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Hepatocyte growth factor receptor signaling
Evading growth suppressors

G1 to S cell cycle control (Homo sapiens)

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G1 to S cell cycle control
Activating invasion and metastasis

Focal adhesion: PI3K-Akt-mTOR-signaling (Homo sapiens)

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Focal adhesion: PI3K-Akt-mTOR-signaling
Enabling replicative immortality

Regulation of Wnt / B-catenin signaling by small molecule compounds (Homo sapiens)

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Regulation of Wnt / B-catenin signaling by small molecule compounds
Inducing angiogenesis

VEGFA-VEGFR2 signaling (Homo sapiens)

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VEGFA-VEGFR2 signaling
Resisting cell death

Apoptosis (Homo sapiens)

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Apoptosis
Deregulating cellular energetics

Glycolysis and gluconeogenesis (Homo sapiens)

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Glycolysis and gluconeogenesis
Genome instability and mutation

Nucleotide excision repair (Homo sapiens)

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Nucleotide excision repair
Tumor promoting inflammation

Chemokine signaling (Homo sapiens)

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Chemokine signaling
Avoiding immune destruction

Type II interferon signaling (Homo sapiens)

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Type II interferon signaling
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