Portal:CPTAC/Hallmarks

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Sustaining proliferative signaling

Ras signaling (Homo sapiens)

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Ras signaling
Evading growth suppressors

Tumor suppressor activity of SMARCB1 (Homo sapiens)

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Tumor suppressor activity of SMARCB1
Activating invasion and metastasis

H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer (Homo sapiens)

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H19, Rb-E2F1, and CDK-beta-catenin in colorectal cancer
Enabling replicative immortality

Wnt signaling (Homo sapiens)

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Wnt signaling
Inducing angiogenesis

PDGF pathway (Homo sapiens)

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PDGF pathway
Resisting cell death

TP53 network (Homo sapiens)

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TP53 network
Deregulating cellular energetics

Hereditary leiomyomatosis and renal cell carcinoma pathway (Homo sapiens)

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Hereditary leiomyomatosis and renal cell carcinoma pathway
Genome instability and mutation

ATR signaling (Homo sapiens)

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ATR signaling
Tumor promoting inflammation

Cytokines and inflammatory response (Homo sapiens)

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Cytokines and inflammatory response
Avoiding immune destruction

Interferon type I signaling (Homo sapiens)

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Interferon type I signaling
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