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• Pathway:WP4415
  ... cers. Activating mutations in RAS are found in approximately one third of human cancers, while ~8% of tumors express an activated form of BRAF (Roberts an ... ... umans, the pathways do show points of significant divergence. Notably, the human genome encodes three Ci homologues, GLI1, 2 and 3 that each play slightly ...
  388 KB (46676 words) - 16:11, 25 January 2021
• Pathway:WP61
  <Comment>DLL4 interacts with NOTCH1 in co-culture of human primary macrophages and a mouse stromal cell.</Comment>
  80 KB (8212 words) - 23:17, 27 February 2025
• Pathway:WP127
  ... <Comment>IL-5 stimulation leads to tyrosine phosphorylation of PTPN11 in human eosinophils.</Comment> <Comment>IL-5 stimulation leads to autophosphorylation of p45 MEK in human eosinophils.</Comment>
  70 KB (7129 words) - 23:05, 30 November 2025
• Pathway:WP364
  ... hosphorylation and activation of ERK1 in AF-10 B cell line,LNCaP cells and human granulosa cells,ES cell line,E14TG2a respectively.</Comment> ... hosphorylation and activation of ERK2 in AF-10 B cell line,LNCaP cells and human granulosa cells,ES cell line,E14TG2a respectively.</Comment>
  89 KB (8624 words) - 23:06, 30 November 2025
• Pathway:WP231
  ... lation with TNF alpha induces the activation and phosphorylation of JNK in human RASFs, HeLa, endometric stromal cells, HUVECs, dendritic cells and 3T3-L1 ... ... <Comment>Stimulation with TNF alpha induces the phosphorylation of ERK in human RASFs, HeLa cells, eosinophils, endometriotic stromal tissue, 3T3-L1 cells ...
  125 KB (12512 words) - 07:33, 5 March 2025
• Pathway:WP493
  <Comment Source="GenMAPP remarks">Converted to human by GenMAPP.org</Comment>
  127 KB (12340 words) - 10:32, 23 May 2021
• Pathway:WP5516
  ... pe="http://www.w3.org/2001/XMLSchema#string">group 3 innate lymphoid cell, human</bp:TERM>
  44 KB (4640 words) - 11:08, 30 October 2025
• Pathway:WP376
  <Comment>Mapping based on name of ortholog human gene.</Comment> <Comment>Identifier based on similar name for ortholog human gene</Comment>
  288 KB (39057 words) - 12:35, 31 July 2025
• Pathway:WP69
  ... >TCR stimulation induces the phosphorylation of MEK2 in DP thymocytes, the human Jurkat T leukemia cell line (clone E6-1)and jurkat T cells.</Comment> ... stimulation induces the phosphorylation of LCK at Tyrosine 192 and 505 in human Jurkat T cell lines and T lymphoblastoid cell line, H9 (TCR/CD3 cross link ...
  110 KB (11290 words) - 08:12, 4 March 2025
• Pathway:WP15
  ... g">Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells.</bp:TITLE> ... atatype="http://www.w3.org/2001/XMLSchema#string">Molecular cloning of the human gene encoding lanosterol synthase from a liver cDNA library.</bp:TITLE>
  604 KB (70685 words) - 07:08, 10 December 2025
• Pathway:WP176
  ... :datatype="http://www.w3.org/2001/XMLSchema#string">Membrane topography of human phosphatidylethanolamine N-methyltransferase.</bp:TITLE> ... string">Relationship of plasma folic acid and status of DNA methylation in human gastric cancer.</bp:TITLE>
  612 KB (76224 words) - 05:41, 9 December 2025
• Pathway:WP722
  <Comment>Coexpression of the human 5-HT(1D) receptor with Galpha(i1), alpha(i2), alpha(i3), or Galpha(o)-prot ... <Comment>Coexpression of the human 5-HT(1D) receptor with Galpha(i1), alpha(i2), alpha(i3), or Galpha(o)-prot ...
  709 KB (96633 words) - 09:44, 19 November 2025
• Pathway:WP968
  ... on leads to tyrosine phosphorylation of Raf-1 and subsequent activation in human eosinophils.</Comment> ... ment>IL-5 stimulation leads to phosphorylation at tyrosine 705 of STAT3 in human eosinophils.</Comment>
  89 KB (8939 words) - 10:35, 26 February 2025
• Pathway:WP976
  ... hosphorylation and activation of ERK1 in AF-10 B cell line,LNCaP cells and human granulosa cells,ES cell line,E14TG2a respectively.</Comment> ... hosphorylation and activation of ERK2 in AF-10 B cell line,LNCaP cells and human granulosa cells,ES cell line,E14TG2a respectively.</Comment>
  102 KB (10131 words) - 11:28, 26 February 2025
• Pathway:WP1011
  ... >TCR stimulation induces the phosphorylation of MEK2 in DP thymocytes, the human Jurkat T leukemia cell line (clone E6-1)and jurkat T cells.</Comment> ... stimulation induces the phosphorylation of LCK at Tyrosine 192 and 505 in human Jurkat T cell lines and T lymphoblastoid cell line, H9 (TCR/CD3 cross link ...
  128 KB (13229 words) - 07:42, 2 March 2025
• Pathway:WP1047
  ... <Comment>Stimulation with TNF alpha induces the phosphorylation of ERK in human RASFs, HeLa cells, eosinophils, endometriotic stromal tissue, 3T3-L1 cells ... ... <Comment>Stimulation with TNF-alpha induces the phosphorylation of ERK in human RASFs, endometrial stromal cells, dendritic cells, B16/F10.9 and 3T3-L1 ad ...
  143 KB (14447 words) - 18:56, 3 March 2025
• Pathway:WP1064
  <Comment>DLL4 interacts with NOTCH1 in co-culture of human primary macrophages and a mouse stromal cell.</Comment>
  93 KB (9673 words) - 18:58, 3 March 2025
• Pathway:WP1075
  ... tp://www.w3.org/2001/XMLSchema#string">Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C ... ... g">Cloning, heterologous expression, and enzymological characterization of human squalene monooxygenase.</bp:TITLE>
  619 KB (77474 words) - 07:12, 10 December 2025
• Pathway:WP1533
  ... tatype="http://www.w3.org/2001/XMLSchema#string">cDNA cloning of mouse and human cholesterol 25-hydroxylases, polytopic membrane proteins that synthesize a ... ... tiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells.</bp:TITLE>
  545 KB (68185 words) - 20:18, 18 December 2025
• Pathway:WP1763
  ... full name: alpha thalassemia/mental retardation syndrome X-linked homolog (human)</Comment> ... ing">Conserved and divergent paths that regulate self-renewal in mouse and human embryonic stem cells</bp:TITLE>
  741 KB (73570 words) - 19:29, 26 April 2023

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