Arylhydrocarbon receptor (AhR) signaling pathway (Bos taurus)

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Description

The aryl hydrocarbon receptor (AhR) is a transcription factor (part of the group of nuclear receptors) that responds to the presence of aromatic hydrocarbons. It regulates genes involved xenobiotic metabolism, e.g. cytochrome P450 enzymes.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2100(74081) with a 92.0% conversion rate.

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Ontology Terms

 

Bibliography

  1. Rowlands JC, Gustafsson JA; ''Aryl hydrocarbon receptor-mediated signal transduction.''; Crit Rev Toxicol, 1997 PubMed Europe PMC Scholia
  2. Bock KW, Köhle C; ''Ah receptor: dioxin-mediated toxic responses as hints to deregulated physiologic functions.''; Biochem Pharmacol, 2006 PubMed Europe PMC Scholia
  3. Haarmann-Stemmann T, Bothe H, Abel J; ''Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AhR) signaling pathways.''; Biochem Pharmacol, 2009 PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
142154view12:41, 6 December 2025EgonwModified description
80804view15:26, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AHRGeneProductENSBTAG00000007746 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000106546
AHRRGeneProductENSBTAG00000026527 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000063438
AIPGeneProductENSBTAG00000010478 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000110711
ALDH3A1GeneProductENSBTAG00000021113 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000108602
ARNTGeneProductENSBTAG00000021037 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:405
BAXGeneProductENSBTAG00000013340 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000087088
CDC37GeneProductENSBTAG00000011699 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000105401
CDKN1AGeneProductENSBTAG00000008353 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000124762
CDKN1BGeneProductENSBTAG00000018254 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000111276
CYP1A1GeneProductENSBTAG00000001021 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140465
CYP1A2GeneProductENSBTAG00000000085 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140505
CYP1B1GeneProductENSBTAG00000010531 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138061
CarcinogenMetaboliteCHEBI:50903 (ChEBI)
EGFRGeneProductENSBTAG00000011628 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000146648
GSTA2GeneProductENSBTAG00000006546 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000244067
HES1GeneProductENSBTAG00000000569 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000114315
HSP90AA1GeneProductENSBTAG00000006270 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000080824
IGFBP1GeneProductENSBTAG00000046768 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000146678
IL2GeneProductENSBTAG00000020883 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000109471
JUNDGeneProduct
JUNGeneProductENSBTAG00000004037 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000177606
NFE2L2GeneProductENSBTAG00000019255 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000116044
NQO1GeneProductENSBTAG00000020632 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000181019
PTGES3GeneProductENSBTAG00000017967 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000110958
SRCGeneProductENSBTAG00000008938 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000197122
TNFGeneProductENSBTAG00000025471 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000232810
UGT1A1GeneProductENSBTAG00000026181 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000241635
UGT1A6GeneProduct
filaggrin GeneProduct

Annotated Interactions

No annotated interactions
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