PPAR signaling pathway (Danio rerio)

From WikiPathways

Revision as of 22:43, 26 July 2017 by Khanspers (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search
Liver / Skeletal muscleNucleuspltpacadlunsaturated fatty acidspparabVLDLChylomicronangpt14slc27a1b9-cis-Retinoic acidslc27a1asaturated fatty acidseicosanoidGluconeogenesisscdcd36zgc:101540Clofibrateslc27a6apoa1aacox3slc27a4thiazolidinedionesfabp3Adipocyokinesignaling pathwayNSAIDsVLDLChylomicronfabp2fabp7bfabp6fabp7afabp1aSkeletal muscle / AdipocyteAdipocyteunsaturated fatty acidsunsaturated fatty acids9-cis-Retinoic acid9-cis-Retinoic acidNSAIDseicosanoidrxrgapparabrxrgapparabrxrgafads2cyp7a1cyp8b1nr1h3cyp27a1.4dbifabp1afabp3slc27a1acd36lplacsbg1acs14bacsbg2acs14aacs11bacs15acs11aacs13bacs16acs13aslc27a4slc27a1bsi:dkey-91i10.3cyp27a1.2scdbehhadhcpt1aacpt1abcpt2acaa1scp2aLipid transportLipogenesisCholesterol metabolismFatty acid transportFatty acid oxidationacox1acadmLipidmetabolismplin2adipoqaadipoqbsorbs1Adipocyte differentiationilkpdpk1bsi:ch211-202a12.4 ubbubcpck1Cell survivalUbiquitinationpck2aqp7zgc:172295LigandTransciption factorTarget gene


Description

new pathway

Please use the New WikiPathways

View approved pathways at the new wikipathways.org. This website will shutdown soon.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. Lehrke M, Lazar MA; ''The many faces of PPARgamma.''; Cell, 2005 PubMed Europe PMC Scholia
  2. Takahashi N, Goto T, Kusudo T, Moriyama T, Kawada T; ''[The structures and functions of peroxisome proliferator-activated receptors (PPARs)].''; Nihon Rinsho, 2005 PubMed Europe PMC Scholia
  3. Mandard S, Müller M, Kersten S; ''Peroxisome proliferator-activated receptor alpha target genes.''; Cell Mol Life Sci, 2004 PubMed Europe PMC Scholia
  4. Hauner H; ''The mode of action of thiazolidinediones.''; Diabetes Metab Res Rev, 2002 PubMed Europe PMC Scholia
  5. Inoue H; ''[Endogenous ligands for PPARs].''; Nihon Rinsho, 2005 PubMed Europe PMC Scholia
  6. Feige JN, Gelman L, Michalik L, Desvergne B, Wahli W; ''From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.''; Prog Lipid Res, 2006 PubMed Europe PMC Scholia
  7. Fujii H; ''[PPARs-mediated intracellular signal transduction].''; Nihon Rinsho, 2005 PubMed Europe PMC Scholia
  8. Desvergne B, Wahli W; ''Peroxisome proliferator-activated receptors: nuclear control of metabolism.''; Endocr Rev, 1999 PubMed Europe PMC Scholia
  9. Savage DB; ''PPAR gamma as a metabolic regulator: insights from genomics and pharmacology.''; Expert Rev Mol Med, 2005 PubMed Europe PMC Scholia
  10. Desvergne B, Michalik L, Wahli W; ''Transcriptional regulation of metabolism.''; Physiol Rev, 2006 PubMed Europe PMC Scholia
  11. Semple RK, Chatterjee VK, O'Rahilly S; ''PPAR gamma and human metabolic disease.''; J Clin Invest, 2006 PubMed Europe PMC Scholia
  12. Takada I, Kato S; ''[PPARs target genes].''; Nihon Rinsho, 2005 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123454view05:05, 28 July 2022EgonwMade a pathway clickable
116902view11:32, 15 May 2021EweitzModified title
106086view11:59, 16 August 2019MaintBotHMDB identifier normalization
93200view17:07, 2 August 2017Khanspersfixed unconnected
93149view23:07, 31 July 2017Khanspersfixed interaction
93067view17:03, 27 July 2017Khanspersfixed interaction
93039view22:52, 26 July 2017KhanspersOntology Term : 'PW:0001356' removed !
93038view22:52, 26 July 2017KhanspersOntology Term : 'peroxisome proliferator-activated receptor signaling pathway' added !
93037view22:52, 26 July 2017KhanspersOntology Term : 'altered peroxisome proliferator-activated receptor signaling pathway' added !
93036view22:52, 26 July 2017KhanspersAdded lit refs
93035view22:44, 26 July 2017KhanspersModified description
93034view22:43, 26 July 2017KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
9-cis-Retinoic acidMetaboliteHMDB02369 (HMDB)
Adipocyokine signaling pathwayPathway
ClofibrateMetaboliteHMDB14774 (HMDB)
GluconeogenesisPathwayWP1356 (WikiPathways)
NSAIDsMetaboliteCHEBI:35475 (ChEBI)
VLDL ChylomicronMetaboliteCHEBI:6495 (ChEBI)
acaa1GeneProductZDB-GENE-040704-48 (ZFIN)
acadlGeneProductZDB-GENE-040426-771 (ZFIN)
acadmGeneProductZDB-GENE-040426-1945 (ZFIN)
acox1GeneProductZDB-GENE-041010-219 (ZFIN)
acox3GeneProductZDB-GENE-040426-2163 (ZFIN)
acs11aGeneProductZDB-GENE-050809-115 (ZFIN)
acs11bGeneProductZDB-GENE-040801-88 (ZFIN)
acs13aGeneProductZDB-GENE-050420-181 (ZFIN)
acs13bGeneProductZDB-GENE-030131-492 (ZFIN)
acs14aGeneProductZDB-GENE-040426-1565 (ZFIN)
acs14bGeneProductZDB-GENE-030131-6493 (ZFIN)
acs15GeneProductZDB-GENE-040912-169 (ZFIN)
acs16GeneProductZDB-GENE-030131-6776 (ZFIN)
acsbg1GeneProductZDB-GENE-110914-219 (ZFIN)
acsbg2GeneProductZDB-GENE-030131-7099 (ZFIN)
adipoqaGeneProductZDB-GENE-080423-2 (ZFIN)
adipoqbGeneProductZDB-GENE-060825-220 (ZFIN)
angpt14GeneProductZDB-GENE-041111-222 (ZFIN)
apoa1aGeneProductZDB-GENE-990415-14 (ZFIN)
aqp7GeneProductZDB-GENE-030131-6461 (ZFIN)
cd36GeneProductZDB-GENE-040718-55 (ZFIN)
cpt1aaGeneProductZDB-GENE-060503-925 (ZFIN)
cpt1abGeneProductZDB-GENE-030131-3250 (ZFIN)
cpt2GeneProductZDB-GENE-030131-6719 (ZFIN)
cyp27a1.2GeneProductZDB-GENE-081104-511 (ZFIN)
cyp27a1.4GeneProductZDB-GENE-030131-1060 (ZFIN)
cyp7a1GeneProductZDB-GENE-040426-1296 (ZFIN)
cyp8b1GeneProductZDB-GENE-040808-53 (ZFIN)
dbiGeneProductZDB-GENE-040426-1861 (ZFIN)
ehhadhGeneProductZDB-GENE-040426-2581 (ZFIN)
eicosanoidMetaboliteCHEBI:23899 (ChEBI)
fabp1aGeneProductZDB-GENE-020318-3 (ZFIN)
fabp2GeneProductZDB-GENE-991019-5 (ZFIN)
fabp3GeneProductZDB-GENE-020318-2 (ZFIN)
fabp6GeneProductZDB-GENE-040625-49 (ZFIN)
fabp7aGeneProductZDB-GENE-000627-1 (ZFIN)
fabp7bGeneProductZDB-GENE-040614-4 (ZFIN)
fads2GeneProductZDB-GENE-011212-1 (ZFIN)
ilkGeneProductZDB-GENE-040426-1435 (ZFIN)
lplGeneProductZDB-GENE-990415-139 (ZFIN)
nr1h3GeneProductZDB-GENE-050410-7 (ZFIN)
pck1GeneProductZDB-GENE-030909-11 (ZFIN)
pck2GeneProductZDB-GENE-040426-2266 (ZFIN)
pdpk1bGeneProductZDB-GENE-040426-1820 (ZFIN)
plin2GeneProductZDB-GENE-050913-12 (ZFIN)
pltpGeneProductZDB-GENE-040801-22 (ZFIN)
pparabGeneProductZDB-GENE-990415-211 (ZFIN)
rxrgaGeneProductZDB-GENE-980526-36 (ZFIN)
saturated fatty acidsMetaboliteCHEBI:26607 (ChEBI)
scdGeneProductZDB-GENE-031106-3 (ZFIN)
scdbGeneProductZDB-GENE-050522-12 (ZFIN)
scp2aGeneProductZDB-GENE-040426-1846 (ZFIN)
si:ch211-202a12.4 GeneProductZDB-GENE-030131-8486 (ZFIN)
si:dkey-91i10.3GeneProductZDB-GENE-081105-124 (ZFIN)
slc27a1aGeneProductZDB-GENE-050320-112 (ZFIN)
slc27a1bGeneProductZDB-GENE-061013-672 (ZFIN)
slc27a4GeneProductZDB-GENE-050417-248 (ZFIN)
slc27a6GeneProductZDB-GENE-060825-27 (ZFIN)
sorbs1GeneProductZDB-GENE-090313-168 (ZFIN)
thiazolidinedionesMetaboliteCHEBI:50864 (ChEBI) Should be thiazolidine derivative
ubbGeneProductZDB-GENE-050411-10 (ZFIN)
ubcGeneProductZDB-GENE-061110-88 (ZFIN)
unsaturated fatty acidsMetaboliteCHEBI:27208 (ChEBI)
zgc:101540GeneProductZDB-GENE-041212-67 (ZFIN)
zgc:172295GeneProductZDB-GENE-080204-72 (ZFIN)

Annotated Interactions

No annotated interactions

Retrieved from "https://oldclassic.wikipathways.org/index.php/Pathway:WP4020"
Personal tools