Nanomaterial-induced inflammasome activation (Homo sapiens)

From WikiPathways

Revision as of 06:13, 8 September 2016 by Torresandon (Talk | contribs)
Jump to: navigation, search
1, 2LysosomeNanomaterial-Associated Molecular Patterns InflammasomeCaspase-1NADPH oxidase 1pro-IL-1bNFKB1Cathepsin BASC NLRP3PotassiumPAMPsCaspase-1 (Fragment)IL1BTLR4IL1BROS productionPotassium


Description

No description

Please use the New WikiPathways

View approved pathways at the new wikipathways.org. This website will shutdown soon.

Quality Tags

Ontology Terms

 

Bibliography

  1. Bhattacharya K, Andón FT, El-Sayed R, Fadeel B; ''Mechanisms of carbon nanotube-induced toxicity: focus on pulmonary inflammation.''; Adv Drug Deliv Rev, 2013 PubMed Europe PMC Scholia
  2. Farrera C, Fadeel B; ''It takes two to tango: Understanding the interactions between engineered nanomaterials and the immune system.''; Eur J Pharm Biopharm, 2015 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
134328view12:51, 20 July 2024EweitzStandardize case
134281view05:21, 20 July 2024EgonwRemoved a template comment
124504view08:41, 3 November 2022JPM van RijnModified description
116457view10:02, 7 May 2021EweitzModified title
110231view14:27, 27 April 2020EgonwNot a mim-conversion
109788view01:37, 1 April 2020AlexanderPicoModified title
109787view01:35, 1 April 2020AlexanderPicoupdated xrefs and layout
106757view13:24, 17 September 2019MaintBotHMDB identifier normalization
94756view15:35, 5 October 2017Mkutmonfix unconnected lines
92318view08:51, 20 May 2017EgonwOntology Term : 'nanomaterial response pathway' added !
92313view08:47, 20 May 2017EgonwOntology Term : 'xenobiotic metabolic pathway' added !
91312view19:08, 26 January 2017KhanspersModified title
89364view06:25, 8 September 2016TorresandonModified description
89363view06:13, 8 September 2016TorresandonPAMPs
89362view06:07, 8 September 2016TorresandonUpdate TLR receptor and necessary stimuli for the activation of the pathway
89305view13:23, 31 August 2016EgonwOntology Term : 'regulatory pathway' added !
89304view13:23, 31 August 2016EgonwOntology Term : 'macrophage' added !
89303view13:22, 31 August 2016EgonwOntology Term : 'PW:0001018' removed !
89302view13:22, 31 August 2016EgonwOntology Term : 'innate immune response pathway' added !
89301view13:21, 31 August 2016EgonwOntology Term : 'immune system disease pathway' added !
89286view13:09, 30 August 2016TorresandonAdd references
89285view13:06, 30 August 2016TorresandonAdd references
89284view12:13, 30 August 2016TorresandonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ASC
Caspase-1 (Fragment)ProteinH0YEC7 (Uniprot-TrEMBL)
Caspase-1ProteinB4DVD8 (Uniprot-TrEMBL)
Cathepsin BProteinE9PCB3 (Uniprot-TrEMBL)
IL1BGeneProductENSG00000125538 (Ensembl)
IL1BProteinP01584 (Uniprot-TrEMBL)
NADPH oxidase 1ProteinA6NGA6 (Uniprot-TrEMBL)
NFKB1GeneProductNFKB1 (HGNC)
NLRP3ProteinA0A024R5Q0 (Uniprot-TrEMBL)
PAMPs
PotassiumMetaboliteHMDB00586 (HMDB)
ROS productionMetaboliteCHEBI:26523 (ChEBI)
TLR4GeneProductENSG00000136869 (Ensembl)
pro-IL-1bProteinP01584 (Uniprot-TrEMBL)

Annotated Interactions

No annotated interactions

Retrieved from "https://oldclassic.wikipathways.org/index.php/Pathway:WP3890"