RIOK1 and RIOK2 in EGFR- and PI3K-mediated tumorigenesis (Homo sapiens)

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1L11 Ribosomal Stress ResponseATORC2RIOK1Akt1foxoRIOK2PtenTumorogenesisPi3KEgfrp53EgfrPi3KPtenfoxoTORC2RIOK1RIOK2Akt1Tumorogenesis


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Read RD, Fenton TR, Gomez GG, Wykosky J, Vandenberg SR, Babic I, Iwanami A, Yang H, Cavenee WK, Mischel PS, Furnari FB, Thomas JB; ''A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma.''; PLoS Genet, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
127936view17:29, 18 January 2024KhanspersOntology Term : 'altered phosphatidylinositol 3-kinase-Akt signaling pathway' added !
127935view17:29, 18 January 2024KhanspersOntology Term : 'glioblastoma' added !
127934view17:25, 18 January 2024Khanspersswapped unconnected pathway nodes for labels
127929view22:11, 17 January 2024Khanspersupdated to Homo sapiens, updated xrefs and description
123360view04:51, 18 July 2022EgonwMade two pathways clickable
108159view10:42, 29 November 2019FehrhartOntology Term : 'cancer' added !
89744view23:50, 29 September 2016KhanspersModified title
89642view23:21, 22 September 2016KhanspersCombined into one diagram
89111view18:41, 22 August 2016AAR&CoDeleted extra comment
89062view06:46, 19 August 2016FehrhartConnected line
88807view22:10, 14 August 2016AAR&CoOntology Term : 'altered stress response pathway' added !
88806view22:09, 14 August 2016AAR&CoOntology Term : 'cancer pathway' added !
88805view22:09, 14 August 2016AAR&CoModified description
88804view22:07, 14 August 2016AAR&CoAdded New Nodes
88803view22:04, 14 August 2016AAR&CoModified description
88799view21:07, 14 August 2016AAR&CoNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Akt1GeneProductFBgn0010379 (Ensembl) AKT Not Specified
EgfrGeneProductFBgn0003731 (Ensembl)
Pi3KGeneProductFBgn0015279 (Ensembl)
PtenGeneProductFBgn0026379 (Ensembl)
RIOK1GeneProductFBgn0036187 (Ensembl)
RIOK2GeneProductFBgn0039306 (Ensembl)
TORC2GeneProductQ3U182 (Uniprot-TrEMBL)
TumorogenesisPathwayIdentifier Not Found
foxoGeneProductFBgn0038197 (Ensembl)
p53GeneProductFBgn0039044 (Ensembl)

Annotated Interactions

No annotated interactions

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