Turbo design of glycolysis (Saccharomyces cerevisiae)
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Description
Many catabolic pathways begin with an ATP-requiring activation step, after which further metabolism yields a surplus of ATP. Such a 'turbo' principle is useful but also contains an inherent risk. This is illustrated by a detailed kinetic analysis of glycolysis in a Saccharomyces cerevisiae mutant.
The model has been converted to GPML using the PathSBML plugin from PathVIsio, importing the model BIOMD0000000253 from the BioModels Database directly. The layout has been improved manually.
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Ontology Terms
Saving...Bibliography
- Teusink B, Walsh MC, van Dam K, Westerhoff HV; ''The danger of metabolic pathways with turbo design.''; Trends Biochem Sci, 1998 PubMed Europe PMC Scholia
History
External references
DataNodes
| View all... |
| Name | Type | Database reference | Comment |
|---|---|---|---|
| ADP | Metabolite | CHEBI:16761 (ChEBI)  | |
| ATP | Metabolite | CHEBI:15422 (ChEBI) | |
| Fru 1,6 P2 | Metabolite | HMDB01058 (HMDB) | |
| Glc | Metabolite | CHEBI:17925 (ChEBI) | |
| HMP | Metabolite | CHEBI:17665 (ChEBI) | |
| Tre 6 P | Metabolite | CHEBI:18283 (ChEBI) |
Annotated Interactions
| View all... |
| Source | Target | Type | Database reference | Comment |
|---|---|---|---|---|
| ADP | SBGN-Production | 13068 (Rhea) | ||
| ADP | lower (WikiPathways) | |||
| ATP | 13068 (Rhea) | |||
| ATP | R00756 (KEGG Reaction) | |||
| ATP | R02848 (KEGG Reaction) | |||
| Fru 1,6 P2 | SBGN-Production | R00756 (KEGG Reaction) | ||
| Fru 1,6 P2 | lower (WikiPathways) | |||
| Glc | R02848 (KEGG Reaction) | |||
| HMP | R00756 (KEGG Reaction) | |||
| HMP | R02848 (KEGG Reaction) | |||
| HMP | SBGN-Production | R02848 (KEGG Reaction) | ||
| SBGN-Production | lower (WikiPathways) | |||
| Tre 6 P | SBGN-Production | R02848 (KEGG Reaction) |
