NAD+ metabolism (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Verdin E; ''NAD⁺ in aging, metabolism, and neurodegeneration.''; Science, 2015 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	137776	view	01:03, 8 March 2025	Khanspers	Modified description
	118983	view	21:10, 6 June 2021	Mkutmon	update layout
	118939	view	22:30, 4 June 2021	Eweitz	Ontology Term : 'nicotinamide adenine dinucleotide metabolic pathway' added !
	118786	view	20:55, 1 June 2021	Khanspers	update metabolites and pathway nodes
	115123	view	19:46, 26 January 2021	Khanspers	new layout and style
	113960	view	23:29, 11 December 2020	Khanspers	Modified description
	113959	view	23:27, 11 December 2020	Khanspers	Removed question marks in gene symbols, spelled out electron transport chain
	112974	view	18:48, 26 October 2020	Khanspers	layout and labels
	106748	view	13:23, 17 September 2019	MaintBot	HMDB identifier normalization
	106654	view	21:16, 12 September 2019	Khanspers	Modified description
	105655	view	05:14, 10 August 2019	Khanspers	Modified description
	94904	view	23:25, 12 October 2017	Khanspers	added lit ref
	94795	view	23:19, 5 October 2017	AlexanderPico	Connected interactions and fixed catalysis layouts
	89859	view	12:26, 6 October 2016	Mkutmon	Modified description
	88175	view	15:53, 29 July 2016	Jmelius	Ontology Term : 'classic metabolic pathway' added !
	85724	view	23:55, 6 June 2016	Khanspers	latest update
	85610	view	22:57, 2 June 2016	Khanspers	Quick edit to datanode annotation or property
	85549	view	23:48, 27 May 2016	AlexanderPico	Quick edit to datanode annotation or property
	85548	view	23:47, 27 May 2016	AlexanderPico	Quick edit to datanode annotation or property
	85541	view	22:43, 27 May 2016	Khanspers	Modified description
	85540	view	22:42, 27 May 2016	Khanspers	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
?NMNAT3	GeneProduct	ENSG00000163864 (Ensembl)
ART	GeneProduct
CD38	GeneProduct	ENSG00000004468 (Ensembl)
CD73	GeneProduct	ENSG00000135318 (Ensembl)
ETC	Pathway
FADH2	Metabolite
FADH	Metabolite	HMDB01197 (HMDB)
Glyceraldehyde 3-phosphate shuttle	Pathway
Glycolysis	Pathway	WP534 (WikiPathways)
L-Tryptophan (TRP)	Metabolite	HMDB00929 (HMDB)
Lactate	Metabolite	HMDB00190 (HMDB)
Malate/aspartate shuttle	Pathway
NADH	Metabolite	HMDB01487 (HMDB)
NAD	Metabolite	HMDB00902 (HMDB)
NADK	GeneProduct	ENSG00000008130 (Ensembl)
NADPH	Metabolite	HMDB00221 (HMDB)
NADP	Metabolite	HMDB00217 (HMDB)
NA	Metabolite	HMDB01488 (HMDB)
NAM	Metabolite	HMDB01406 (HMDB)
NAMN	Metabolite	HMDB01132 (HMDB)
NAMPT	GeneProduct	ENSG00000105835 (Ensembl)
NMN	Metabolite	13553 (Chemspider)
NMNAT1	GeneProduct	ENSG00000173614 (Ensembl)
NMNAT2	GeneProduct	ENSG00000157064 (Ensembl)
NR	Metabolite	HMDB00855 (HMDB)
NRK	GeneProduct	ENSG00000123572 (Ensembl)
Nicotinic acid (NA)	Metabolite	HMDB01488 (HMDB)
PARP1	GeneProduct	ENSG00000143799 (Ensembl)
PRPP	Metabolite	HMDB00280 (HMDB)
Pyruvate	Metabolite	HMDB00243 (HMDB)
SIRT1	GeneProduct	ENSG00000096717 (Ensembl)
SIRT2	GeneProduct	ENSG00000068903 (Ensembl)
SIRT3	GeneProduct	ENSG00000142082 (Ensembl)
SIRT4	GeneProduct	ENSG00000089163 (Ensembl)
SIRT5	GeneProduct	ENSG00000124523 (Ensembl)
SIRT6	GeneProduct	ENSG00000077463 (Ensembl)
SIRT7	GeneProduct	ENSG00000187531 (Ensembl)
TCA Cycle	Pathway	WP73 (WikiPathways)
TRP	Metabolite	HMDB00929 (HMDB)
dATP	Metabolite	HMDB01532 (HMDB)

Annotated Interactions

No annotated interactions