RuMP cycle, oxidative branch of the pentose phosphate pathway and formaldehyde assimilation (Saccharomyces cerevisiae)

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H+D-arabino-3-hexulose 6-phosphateformateNADCO2H+NADNADNADPH+CO26-phospho-gluconateH2OGND2ribulose-5-phosphateNADHformaldehydeNADPHfructose-6-phosphateNADHglucose-6-phosphateFDH1formaldehydeNADHGND1PGI1


Description

No description

Comments

GenMAPP remarks 
Based on http://pathway.yeastgenome.org/biocyc/

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Ontology Terms

 

Bibliography

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  1. Grey M, Schmidt M, Brendel M; ''Overexpression of ADH1 confers hyper-resistance to formaldehyde in Saccharomyces cerevisiae.''; Curr Genet, 1996 PubMed Europe PMC Scholia
  2. Degrassi G, Uotila L, Klima R, Venturi V; ''Purification and properties of an esterase from the yeast Saccharomyces cerevisiae and identification of the encoding gene.''; Appl Environ Microbiol, 1999 PubMed Europe PMC Scholia
  3. Achkor H, Díaz M, Fernández MR, Biosca JA, Parés X, Martínez MC; ''Enhanced formaldehyde detoxification by overexpression of glutathione-dependent formaldehyde dehydrogenase from Arabidopsis.''; Plant Physiol, 2003 PubMed Europe PMC Scholia
  4. Sinha A, Maitra PK; ''Induction of specific enzymes of the oxidative pentose phosphate pathway by glucono-delta-lactone in Saccharomyces cerevisiae.''; J Gen Microbiol, 1992 PubMed Europe PMC Scholia
  5. Stanford DR, Whitney ML, Hurto RL, Eisaman DM, Shen WC, Hopper AK; ''Division of labor among the yeast Sol proteins implicated in tRNA nuclear export and carbohydrate metabolism.''; Genetics, 2004 PubMed Europe PMC Scholia
  6. Nogae I, Johnston M; ''Isolation and characterization of the ZWF1 gene of Saccharomyces cerevisiae, encoding glucose-6-phosphate dehydrogenase.''; Gene, 1990 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
140363view08:58, 15 August 2025EgonwMore unicode
139547view06:39, 21 June 2025EgonwWater with unicode
111625view04:34, 31 August 2020EgonwModified title
96437view07:53, 15 March 2018EgonwReplaced another secondary ChEBI identifier with a primary identifier.
96370view09:28, 10 March 2018EgonwReplaced secondary ChEBI identifiers with primary identifiers.
94154view13:21, 24 August 2017DeSlAdded lit. refs from PW417 to this PW
94153view13:17, 24 August 2017DeSlOntology Term : 'pentose phosphate pathway - oxidative phase' added !
94152view13:16, 24 August 2017DeSlAdded visualisation for Oxidative Branch of the Pentose Phosphate Pathway, in order to remove double content from WP417
94151view13:14, 24 August 2017DeSlModified title
94147view11:59, 24 August 2017DeSlAnnotated last missing node (CO2)
94146view11:57, 24 August 2017DeSlAdded missing IDs
94145view11:47, 24 August 2017DeSlModified description
94144view11:45, 24 August 2017DeSlAdded node for 6-phosphone-D-glucono-lactone in cycle, which was missing before. Added literature references. Combined two lose PWs into one. Added nodes between formaldehyde and formate reaction, which where missing before.
89664view05:47, 24 September 2016EgonwReplace the CAS number of the salt with that of just the metabolite.
71344view18:01, 17 October 2013MaintBotAutomated update of data sources
71015view19:37, 22 September 2013EgonwConverted metabolite Labelss into DataNodes and added a few ChemSpider IDs.
69855view17:13, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
69614view20:33, 8 July 2013MaintBotUpdated to 2013 gpml schema
67631view11:35, 26 June 2013DdiglesOntology Term : 'RuMP pathway of formaldehyde assimilation' added !
41847view04:50, 2 March 2011MaintBotRemoved redundant pathway information and comments
21377view11:31, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:RuMP cycle Formaldehyde Assimilation]] moved to [[Pathway:WP332]]: Moved to stable identifier
12836view08:04, 17 May 2008MaintBotautomated metabolite conversion
8912view14:12, 7 January 2008MaintBotAdded to category $category
8910view14:12, 7 January 2008J.HeckmanUploaded new pathway

External references

DataNodes

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NameTypeDatabase referenceComment
FDH1GeneProductS000005915 (SGD)
GND1GeneProductS000001226 (SGD)
GND2GeneProductS000003488 (SGD)
NADH53-84-9 (CAS)
NADPH2646-71-1 (CAS)
PGI1GeneProductS000000400 (SGD)
formaldehyde50-00-0 (CAS)
fructose-6-phosphate643-13-0 (CAS)
glucose-6-phosphate59-56-3 (CAS)
ribulose-5-phosphate4151-19-3 (CAS)

Annotated Interactions

No annotated interactions
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