Iron homeostasis (Mus musculus)

Revision as of 10:58, 26 June 2013 by Ddigles (Talk | contribs)

Description

Iron is nessisary for all mammalian cells but is also toxic in excess. This pathway shows the regulation of iron between a cell and the blood stream.

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Revision	Action	Time	User	Comment
142309	view	10:53, 1 January 2026	Egonw	mim-translocation
126400	view	15:38, 26 April 2023	Egonw	License is CCZero
117909	view	10:32, 23 May 2021	Eweitz	Modified title
106857	view	13:33, 17 September 2019	MaintBot	HMDB identifier normalization
72018	view	12:38, 24 October 2013	Mkutmon	fixed unconnected lines
71718	view	20:15, 17 October 2013	MaintBot	Automated update of data sources
67413	view	10:58, 26 June 2013	Ddigles	Ontology Term : 'iron homeostasis pathway' added !
60840	view	11:45, 29 March 2013	Egonw	Fixed two iron metabolites which were annotated as GeneProduct.
59023	view	20:40, 21 February 2013	MaintBot	Updated Ensembl and UniProt data source
43784	view	20:54, 27 July 2011	Samuel Sklar	Modified description
43783	view	20:45, 27 July 2011	Samuel Sklar	Specify description
41260	view	00:20, 2 March 2011	MaintBot	Removed redundant pathway information and comments
38148	view	19:14, 17 August 2010	Khanspers	Modified categories
38130	view	11:02, 16 August 2010	MartijnVanIersel	New pathway

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Name	Type	Database reference
BMP1/2/4/9	GeneProduct
BMPR-1	GeneProduct
Ferroportin	GeneProduct	ENSMUSG00000025993 (Ensembl)
Fth1	GeneProduct	14319 (Entrez Gene)
Ftl1	GeneProduct	ENSMUSG00000050708 (Ensembl)
Hfe	GeneProduct	ENSMUSG00000006611 (Ensembl)
IL-1	GeneProduct	ENSMUSG00000027399 (Ensembl)
IL-6	GeneProduct	ENSMUSG00000025746 (Ensembl)
IL1R	GeneProduct
IL6R	GeneProduct	ENSMUSG00000027947 (Ensembl)
Ireb2	GeneProduct	ENSMUSG00000032293 (Ensembl)
Iron	Metabolite	HMDB00692 (HMDB)
JAK1/2	GeneProduct
SMAD-1/5/8	GeneProduct
STAT3	GeneProduct
Tnf	GeneProduct	ENSMUSG00000024401 (Ensembl)
Transferrin	GeneProduct	ENSMUSG00000032554 (Ensembl)
Trfr1	GeneProduct
Trfr2	GeneProduct	ENSMUSG00000029716 (Ensembl)
cMyc	GeneProduct
hemojuvelin	GeneProduct	ENSMUSG00000038403 (Ensembl)
hepcidin-2	GeneProduct	ENSMUSG00000056978 (Ensembl)
hepcidin	GeneProduct	ENSMUSG00000050440 (Ensembl)

No annotated interactions