Toll-like receptor signaling pathway (Bos taurus)

From WikiPathways

Revision as of 00:03, 10 May 2013 by MaintBot (Talk | contribs)
Jump to: navigation, search
biosynthesis+pLipoarabinomannaneffectsChemotacticdsRNANK cell)+pCpG DNA+pUbiquitin mediated proteolysis+p+p+pIKKeffectscoagulation cascadesssRNAPeptidoglycan(G+)Antiviral effects+T cell stimulationeffects+pCostimulatory moleculesComplement and+pMyD88-dependent pathwayDegradationZymosan (Yeast)+pLPS(G-)+(T cell)Autocrine / Paracrine+pChemotacticMyD88-independent pathwayCytokine-UnmethylatedSpecific pathwayin pDCsProinflammatory+p+p(anti-viral compounds)(Neutrophil, immature DC,cytokine receptor+pLipopolysaccharideEndosomeInflammatory cytokinesApoptosisJak-STAT signaling pathwayFlagellar assemblyDNAImidazoquinolinLipoprotein+pMAPK signaling pathwayInflammatory cytokinesFlagellin+p(Mycobacteria)interactionTRAF6LOC100137872IFNA17PIK3R3TRAF3CD86MAP3K7IP1TLR8IFNA10FOSIRAK1CD14JUNMYD88MAP2K6MAPK11IFNB1SPP1MAP2K2TLR7MAP2K1TLR2IFNA7IL6IFNA16MYD88IFNA14AKT1TICAM2TOLLIPIL8CD40CXCL9STAT1IFNAR2MYD88IRAK4IRF5PIK3R5MAPK1TLR1IL12BCCL3IFNB1MAP3K7CD80MAP3K8RAC1MAPK8MAPK14IKBKGCCL5CXCL11IKBKEMAP3K7IP2NFKB1TIRAPCCL4MAPK13IL1BPIK3CGCXCL10MAP2K4IRAK4IL12AIFNB1PIK3CBNFKB2IRF7CHUKAKT2IFNA6TIRAPTLR9TNFLBPIFNA4IKBKBIFNA5TBK1TRAF6MAPK9PIK3CDPIK3R1MAPK10RELAFADDIRAK1CHUKIFNA2TLR6TRAF6PIK3R2IFNAR1MAP2K7IRF3IFNA1IFNA8TLR3NFKB1CASP8TLR4TLR2PIK3CAIFNA21MAPK12LY96MAPK3RIPK1MAP2K3TICAM1MYD88IFNA13TLR5NFKBIA


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP75(r30264) with a 82% conversion rate.

Please use the New WikiPathways

View approved pathways at the new wikipathways.org. This website will shutdown soon.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
141890view06:19, 26 November 2025EgonwModified description
137516view18:59, 3 March 2025KhanspersModified description
122566view10:33, 16 April 2022EgonwMade a pathway clickable
115321view09:12, 13 February 2021EgonwMade four pathways clickable
80730view15:23, 30 June 2015Mkutmonhomology conversion
63387view00:03, 10 May 2013MaintBotUpdated to 2013 gpml schema
40560view19:32, 1 March 2011MaintBotRemoved redundant pathway information and comments
33798view00:15, 9 December 2009MaintBotAutomatic update of empty xrefs
32525view12:57, 17 August 2009MaintBotFixed text labels
32211view12:43, 15 August 2009MaintBotFixed text labels
31699view11:49, 14 August 2009MaintBotFixed group labels
31223view19:42, 13 August 2009MaintBotFixed text labels
30636view22:28, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct280991 (Entrez Gene) Original kegg element: gene;60;hsa:10000 hsa:207 hsa:208
AKT2GeneProduct534923 (Entrez Gene) Original kegg element: gene;60;hsa:10000 hsa:207 hsa:208
CASP8GeneProduct507481 (Entrez Gene) Original kegg element: gene;87;hsa:841
CCL3GeneProduct282170 (Entrez Gene) Original kegg element: gene;44;hsa:6348
CCL4GeneProduct414347 (Entrez Gene) Original kegg element: gene;38;hsa:6351
CCL5GeneProduct327712 (Entrez Gene) Original kegg element: gene;58;hsa:6352
CD14GeneProduct281048 (Entrez Gene) Original kegg element: gene;84;hsa:929
CD40GeneProduct286849 (Entrez Gene) Original kegg element: gene;29;hsa:958
CD80GeneProduct407131 (Entrez Gene) Original kegg element: gene;69;hsa:941
CD86GeneProduct414345 (Entrez Gene) Original kegg element: gene;28;hsa:942
CHUKGeneProduct281073 (Entrez Gene) Original kegg element: gene;42;hsa:1147
CXCL10GeneProduct615107 (Entrez Gene) Original kegg element: gene;25;hsa:3627
CXCL11GeneProduct516104 (Entrez Gene) Original kegg element: gene;23;hsa:6373
CXCL9GeneProduct513990 (Entrez Gene) Original kegg element: gene;24;hsa:4283
FADDGeneProduct493720 (Entrez Gene) Original kegg element: gene;56;hsa:8772
FOSGeneProduct280795 (Entrez Gene) Original kegg element: gene;35;hsa:2353 hsa:3725
IFNA10GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA1GeneProduct281843 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA13GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA14GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA16GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA17GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA2GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA21GeneProduct282256 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA4GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA5GeneProduct281844 (Entrez Gene) Original kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA6GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA7GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNA8GeneProductOriginal kegg element: gene;27;hsa:3439 hsa:3440 hsa:3441 hsa:3442 hsa:3443 hsa:3444 hsa:3445 hsa:3446 hsa:3447 hsa:3448 hsa:3449 hsa:3451 hsa:3452
IFNAR1GeneProduct282257 (Entrez Gene) Original kegg element: gene;49;hsa:3454 hsa:3455
IFNAR2GeneProduct282258 (Entrez Gene) Original kegg element: gene;49;hsa:3454 hsa:3455
IFNB1GeneProduct281845 (Entrez Gene) Original kegg element: gene;1;hsa:3456
IKBKBGeneProduct281854 (Entrez Gene) Original kegg element: gene;36;hsa:3551
IKBKEGeneProduct533216 (Entrez Gene) Original kegg element: gene;54;hsa:9641
IKBKGGeneProduct281855 (Entrez Gene) Original kegg element: gene;85;hsa:8517
IL12AGeneProduct281856 (Entrez Gene) Original kegg element: gene;45;hsa:3592 hsa:3593
IL12BGeneProduct281857 (Entrez Gene) Original kegg element: gene;45;hsa:3592 hsa:3593
IL1BGeneProduct281251 (Entrez Gene) Original kegg element: gene;51;hsa:3553
IL6GeneProduct280826 (Entrez Gene) Original kegg element: gene;57;hsa:3569
IL8GeneProduct280828 (Entrez Gene) Original kegg element: gene;43;hsa:3576
IRAK1GeneProduct533953 (Entrez Gene) Original kegg element: gene;41;hsa:3654
IRAK4GeneProduct533692 (Entrez Gene) Original kegg element: gene;86;hsa:51135
IRF3GeneProduct516979 (Entrez Gene) Original kegg element: gene;67;hsa:3661
IRF5GeneProduct615340 (Entrez Gene) Original kegg element: gene;21;hsa:3663
IRF7GeneProduct100125591 (Entrez Gene) Original kegg element: gene;20;hsa:3665
JUNGeneProduct280831 (Entrez Gene) Original kegg element: gene;35;hsa:2353 hsa:3725
LBPGeneProduct512242 (Entrez Gene) Original kegg element: gene;77;hsa:3929
LOC100137872GeneProduct100137872 (Entrez Gene) Original kegg element: gene;60;hsa:10000 hsa:207 hsa:208
LY96GeneProduct613753 (Entrez Gene) Original kegg element: gene;71;hsa:23643
MAP2K1GeneProduct533199 (Entrez Gene) Original kegg element: gene;12;hsa:5604 hsa:5605
MAP2K2GeneProduct510434 (Entrez Gene) Original kegg element: gene;12;hsa:5604 hsa:5605
MAP2K3GeneProduct516039 (Entrez Gene) Original kegg element: gene;65;hsa:5606 hsa:5608
MAP2K4GeneProduct526469 (Entrez Gene) Original kegg element: gene;63;hsa:5609 hsa:6416
MAP2K6GeneProduct286883 (Entrez Gene) Original kegg element: gene;65;hsa:5606 hsa:5608
MAP2K7GeneProduct787278 (Entrez Gene) Original kegg element: gene;63;hsa:5609 hsa:6416
MAP3K7GeneProduct529146 (Entrez Gene) Original kegg element: gene;37;hsa:6885
MAP3K7IP1GeneProduct519958 (Entrez Gene) Original kegg element: gene;59;hsa:10454
MAP3K7IP2GeneProduct540203 (Entrez Gene) Original kegg element: gene;61;hsa:23118
MAP3K8GeneProduct535622 (Entrez Gene) Original kegg element: gene;13;hsa:1326
MAPK10GeneProduct537631 (Entrez Gene) Original kegg element: gene;50;hsa:5599 hsa:5601 hsa:5602
MAPK11GeneProduct618906 (Entrez Gene) Original kegg element: gene;40;hsa:1432 hsa:5600 hsa:5603 hsa:6300
MAPK12GeneProduct512943 (Entrez Gene) Original kegg element: gene;40;hsa:1432 hsa:5600 hsa:5603 hsa:6300
MAPK1GeneProduct327672 (Entrez Gene) Original kegg element: gene;11;hsa:5594 hsa:5595
MAPK13GeneProduct535327 (Entrez Gene) Original kegg element: gene;40;hsa:1432 hsa:5600 hsa:5603 hsa:6300
MAPK14GeneProduct534492 (Entrez Gene) Original kegg element: gene;40;hsa:1432 hsa:5600 hsa:5603 hsa:6300
MAPK3GeneProduct531391 (Entrez Gene) Original kegg element: gene;11;hsa:5594 hsa:5595
MAPK8GeneProduct539941 (Entrez Gene) Original kegg element: gene;50;hsa:5599 hsa:5601 hsa:5602
MAPK9GeneProduct534125 (Entrez Gene) Original kegg element: gene;50;hsa:5599 hsa:5601 hsa:5602
MYD88GeneProduct444881 (Entrez Gene) Original kegg element: gene;47;hsa:4615
NFKB1GeneProduct616115 (Entrez Gene) Original kegg element: gene;14;hsa:4790
NFKB2GeneProduct526392 (Entrez Gene) Original kegg element: gene;10;hsa:4790 hsa:4791 hsa:5970
NFKBIAGeneProduct282291 (Entrez Gene) Original kegg element: gene;64;hsa:4792
PIK3CAGeneProduct282306 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
PIK3CBGeneProduct517948 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
PIK3CDGeneProduct504531 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
PIK3CGGeneProduct530001 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
PIK3R1GeneProduct282307 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
PIK3R2GeneProduct282308 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
PIK3R3GeneProduct286865 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
PIK3R5GeneProduct614838 (Entrez Gene) Original kegg element: gene;55;hsa:23533 hsa:5290 hsa:5291 hsa:5293 hsa:5294 hsa:5295 hsa:5296 hsa:8503
RAC1GeneProduct281440 (Entrez Gene) Original kegg element: gene;48;hsa:5879
RELAGeneProduct508233 (Entrez Gene) Original kegg element: gene;10;hsa:4790 hsa:4791 hsa:5970
RIPK1GeneProduct504727 (Entrez Gene) Original kegg element: gene;17;hsa:8737
SPP1GeneProduct281499 (Entrez Gene) Original kegg element: gene;15;hsa:6696
STAT1GeneProduct510814 (Entrez Gene) Original kegg element: gene;62;hsa:6772
TBK1GeneProduct533141 (Entrez Gene) Original kegg element: gene;52;hsa:29110
TICAM1GeneProduct510427 (Entrez Gene) Original kegg element: gene;82;hsa:148022
TICAM2GeneProduct539350 (Entrez Gene) Original kegg element: gene;80;hsa:353376
TIRAPGeneProduct531079 (Entrez Gene) Original kegg element: gene;83;hsa:114609
TLR1GeneProduct574090 (Entrez Gene) Original kegg element: gene;75;hsa:7096
TLR2GeneProduct281534 (Entrez Gene) Original kegg element: gene;74;hsa:7097
TLR3GeneProduct281535 (Entrez Gene) Original kegg element: gene;73;hsa:7098
TLR4GeneProduct281536 (Entrez Gene) Original kegg element: gene;79;hsa:7099
TLR5GeneProduct444870 (Entrez Gene) Original kegg element: gene;72;hsa:7100
TLR6GeneProduct407237 (Entrez Gene) Original kegg element: gene;76;hsa:10333
TLR7GeneProduct493686 (Entrez Gene) Original kegg element: gene;39;hsa:51284 hsa:51311
TLR8GeneProduct532262 (Entrez Gene) Original kegg element: gene;39;hsa:51284 hsa:51311
TLR9GeneProduct282602 (Entrez Gene) Original kegg element: gene;78;hsa:54106
TNFGeneProduct280943 (Entrez Gene) Original kegg element: gene;66;hsa:7124
TOLLIPGeneProduct539480 (Entrez Gene) Original kegg element: gene;81;hsa:54472
TRAF3GeneProduct506182 (Entrez Gene) Original kegg element: gene;16;hsa:7187
TRAF6GeneProduct539124 (Entrez Gene) Original kegg element: gene;53;hsa:7189

Annotated Interactions

No annotated interactions
Retrieved from "https://oldclassic.wikipathways.org/index.php/Pathway:WP1067"
Personal tools