Opioid signaling (Homo sapiens)

From WikiPathways

Revision as of 23:50, 4 March 2011 by MaintBot (Talk | contribs)
(diff) ←Older revision | Current revision (diff) | Newer revision→ (diff)
Jump to: navigation, search


Description

No description

Please use the New WikiPathways

View approved pathways at the new wikipathways.org. This website will shutdown soon.

Quality Tags

Ontology Terms

 

Bibliography

View all...
  1. Bilbao A, Parkitna JR, Engblom D, Perreau-Lenz S, Sanchis-Segura C, Schneider M, Konopka W, Westphal M, Breen G, Desrivieres S, Klugmann M, Guindalini C, Vallada H, Laranjeira R, de Fonseca FR, Schumann G, Schütz G, Spanagel R.; ''Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine.''; PubMed Europe PMC Scholia
  2. Chatila T, Anderson KA, Ho N, Means AR.; ''A unique phosphorylation-dependent mechanism for the activation of Ca2+/calmodulin-dependent protein kinase type IV/GR.''; PubMed Europe PMC Scholia
  3. Huston E, Lumb S, Russell A, Catterall C, Ross AH, Steele MR, Bolger GB, Perry MJ, Owens RJ, Houslay MD.; ''Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.''; PubMed Europe PMC Scholia
  4. Gonzalez GA, Montminy MR.; ''Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133.''; PubMed Europe PMC Scholia
  5. Vandeput F, Wolda SL, Krall J, Hambleton R, Uher L, McCaw KN, Radwanski PB, Florio V, Movsesian MA.; ''Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes.''; PubMed Europe PMC Scholia
  6. Li W, Yu ZX, Kotin RM.; ''Profiles of PrKX expression in developmental mouse embryo and human tissues.''; PubMed Europe PMC Scholia
  7. Ekholm D, Belfrage P, Manganiello V, Degerman E.; ''Protein kinase A-dependent activation of PDE4 (cAMP-specific cyclic nucleotide phosphodiesterase) in cultured bovine vascular smooth muscle cells.''; PubMed Europe PMC Scholia
  8. Börsch-Haubold AG, Bartoli F, Asselin J, Dudler T, Kramer RM, Apitz-Castro R, Watson SP, Gelb MH.; ''Identification of the phosphorylation sites of cytosolic phospholipase A2 in agonist-stimulated human platelets and HeLa cells.''; PubMed Europe PMC Scholia
  9. Yamamori E, Asai M, Yoshida M, Takano K, Itoi K, Oiso Y, Iwasaki Y.; ''Calcium/calmodulin kinase IV pathway is involved in the transcriptional regulation of the corticotropin-releasing hormone gene promoter in neuronal cells.''; PubMed Europe PMC Scholia
  10. Gu C, Cooper DM.; ''Calmodulin-binding sites on adenylyl cyclase type VIII.''; PubMed Europe PMC Scholia
  11. Oldham WM, Van Eps N, Preininger AM, Hubbell WL, Hamm HE.; ''Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins.''; PubMed Europe PMC Scholia
  12. Gerhardt MA, Neubig RR.; ''Multiple Gi protein subtypes regulate a single effector mechanism.''; PubMed Europe PMC Scholia
  13. Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ, Huganir RL, Hemmings HC, Nairn AC, Greengard P.; ''Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons.''; PubMed Europe PMC Scholia
  14. Evans JH, Spencer DM, Zweifach A, Leslie CC.; ''Intracellular calcium signals regulating cytosolic phospholipase A2 translocation to internal membranes.''; PubMed Europe PMC Scholia
  15. Goraya TA, Masada N, Ciruela A, Willoughby D, Clynes MA, Cooper DM.; ''Kinetic properties of Ca2+/calmodulin-dependent phosphodiesterase isoforms dictate intracellular cAMP dynamics in response to elevation of cytosolic Ca2+.''; PubMed Europe PMC Scholia
  16. Goraya TA, Masada N, Ciruela A, Cooper DM.; ''Sustained entry of Ca2+ is required to activate Ca2+-calmodulin-dependent phosphodiesterase 1A.''; PubMed Europe PMC Scholia
  17. Krasel C, Dammeier S, Winstel R, Brockmann J, Mischak H, Lohse MJ.; ''Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.''; PubMed Europe PMC Scholia
  18. Dessauer CW, Gilman AG.; ''Purification and characterization of a soluble form of mammalian adenylyl cyclase.''; PubMed Europe PMC Scholia
  19. Reed KA, Tucker DE, Aloulou A, Adler D, Ghomashchi F, Gelb MH, Leslie CC, Oates JA, Boutaud O.; ''Functional characterization of mutations in inherited human cPLA₂ deficiency.''; PubMed Europe PMC Scholia
  20. Ahn JH, Sung JY, McAvoy T, Nishi A, Janssens V, Goris J, Greengard P, Nairn AC.; ''The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A.''; PubMed Europe PMC Scholia
  21. Taussig R, Tang WJ, Hepler JR, Gilman AG.; ''Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.''; PubMed Europe PMC Scholia
  22. Li X, Li HP, Amsler K, Hyink D, Wilson PD, Burrow CR.; ''PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis.''; PubMed Europe PMC Scholia
  23. Wall MA, Coleman DE, Lee E, Iñiguez-Lluhi JA, Posner BA, Gilman AG, Sprang SR.; ''The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2.''; PubMed Europe PMC Scholia
  24. Kleuss C, Raw AS, Lee E, Sprang SR, Gilman AG.; ''Mechanism of GTP hydrolysis by G-protein alpha subunits.''; PubMed Europe PMC Scholia
  25. Nishi A, Bibb JA, Matsuyama S, Hamada M, Higashi H, Nairn AC, Greengard P.; ''Regulation of DARPP-32 dephosphorylation at PKA- and Cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A.''; PubMed Europe PMC Scholia
  26. Taussig R, Iñiguez-Lluhi JA, Gilman AG.; ''Inhibition of adenylyl cyclase by Gi alpha.''; PubMed Europe PMC Scholia
  27. Wang JB, Johnson PS, Persico AM, Hawkins AL, Griffin CA, Uhl GR.; ''Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment.''; PubMed Europe PMC Scholia
  28. Zigman JM, Westermark GT, LaMendola J, Boel E, Steiner DF.; ''Human G(olf) alpha: complementary deoxyribonucleic acid structure and expression in pancreatic islets and other tissues outside the olfactory neuroepithelium and central nervous system.''; PubMed Europe PMC Scholia
  29. Liang Z, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX.; ''Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain.''; PubMed Europe PMC Scholia
  30. Francken BJ, Jurzak M, Vanhauwe JF, Luyten WH, Leysen JE.; ''The human 5-ht5A receptor couples to Gi/Go proteins and inhibits adenylate cyclase in HEK 293 cells.''; PubMed Europe PMC Scholia
  31. James MA, Lu Y, Liu Y, Vikis HG, You M.; ''RGS17, an overexpressed gene in human lung and prostate cancer, induces tumor cell proliferation through the cyclic AMP-PKA-CREB pathway.''; PubMed Europe PMC Scholia
  32. Lambright DG, Noel JP, Hamm HE, Sigler PB.; ''Structural determinants for activation of the alpha-subunit of a heterotrimeric G protein.''; PubMed Europe PMC Scholia
  33. Sette C, Conti M.; ''Phosphorylation and activation of a cAMP-specific phosphodiesterase by the cAMP-dependent protein kinase. Involvement of serine 54 in the enzyme activation.''; PubMed Europe PMC Scholia
  34. Gullingsrud J, Kim C, Taylor SS, McCammon JA.; ''Dynamic binding of PKA regulatory subunit RI alpha.''; PubMed Europe PMC Scholia
  35. Di Pasquale G, Stacey SN.; ''Adeno-associated virus Rep78 protein interacts with protein kinase A and its homolog PRKX and inhibits CREB-dependent transcriptional activation.''; PubMed Europe PMC Scholia
  36. Saidak Z, Blake-Palmer K, Hay DL, Northup JK, Glass M.; ''Differential activation of G-proteins by mu-opioid receptor agonists.''; PubMed Europe PMC Scholia
  37. Walaas SI, Aswad DW, Greengard P.; ''A dopamine- and cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions.''; PubMed Europe PMC Scholia
  38. Alt A, Clark MJ, Woods JH, Traynor JR.; ''Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells.''; PubMed Europe PMC Scholia
  39. Hemmings HC, Williams KR, Konigsberg WH, Greengard P.; ''DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. I. Amino acid sequence around the phosphorylated threonine.''; PubMed Europe PMC Scholia
  40. Murakami M, Taketomi Y, Sato H, Yamamoto K.; ''Secreted phospholipase A2 revisited.''; PubMed Europe PMC Scholia
  41. Hemmings HC, Greengard P, Tung HY, Cohen P.; ''DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1.''; PubMed Europe PMC Scholia
  42. Lin LL, Wartmann M, Lin AY, Knopf JL, Seth A, Davis RJ.; ''cPLA2 is phosphorylated and activated by MAP kinase.''; PubMed Europe PMC Scholia
  43. Hamm HE.; ''The many faces of G protein signaling.''; PubMed Europe PMC Scholia
  44. Chuang TT, Paolucci L, De Blasi A.; ''Inhibition of G protein-coupled receptor kinase subtypes by Ca2+/calmodulin.''; PubMed Europe PMC Scholia
  45. Levay K, Satpaev DK, Pronin AN, Benovic JL, Slepak VZ.; ''Localization of the sites for Ca2+-binding proteins on G protein-coupled receptor kinases.''; PubMed Europe PMC Scholia
  46. Berstein G, Blank JL, Jhon DY, Exton JH, Rhee SG, Ross EM.; ''Phospholipase C-beta 1 is a GTPase-activating protein for Gq/11, its physiologic regulator.''; PubMed Europe PMC Scholia
  47. Schulz S, Mayer D, Pfeiffer M, Stumm R, Koch T, Höllt V.; ''Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375.''; PubMed Europe PMC Scholia
  48. Martin-Kleiner I, Balog T, Gabrilovac J.; ''Signal transduction induced by opioids in immune cells: a review.''; PubMed Europe PMC Scholia
  49. Régnauld KL, Leteurtre E, Gutkind SJ, Gespach CP, Emami S.; ''Activation of adenylyl cyclases, regulation of insulin status, and cell survival by G(alpha)olf in pancreatic beta-cells.''; PubMed Europe PMC Scholia
  50. Clark JD, Lin LL, Kriz RW, Ramesha CS, Sultzman LA, Lin AY, Milona N, Knopf JL.; ''A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP.''; PubMed Europe PMC Scholia
  51. Dessauer CW, Chen-Goodspeed M, Chen J.; ''Mechanism of Galpha i-mediated inhibition of type V adenylyl cyclase.''; PubMed Europe PMC Scholia
  52. King MM, Huang CY, Chock PB, Nairn AC, Hemmings HC, Chan KF, Greengard P.; ''Mammalian brain phosphoproteins as substrates for calcineurin.''; PubMed Europe PMC Scholia
  53. Caricasole A, Sala C, Roncarati R, Formenti E, Terstappen GC.; ''Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).''; PubMed Europe PMC Scholia
  54. Nagakura A, Takagi N, Takeo S.; ''Impairment of cerebral cAMP-mediated signal transduction system and of spatial memory function after microsphere embolism in rats.''; PubMed Europe PMC Scholia
  55. Standifer KM, Pasternak GW.; ''G proteins and opioid receptor-mediated signalling.''; PubMed Europe PMC Scholia
  56. Chen TY, Illing M, Molday LL, Hsu YT, Yau KW, Molday RS.; ''Subunit 2 (or beta) of retinal rod cGMP-gated cation channel is a component of the 240-kDa channel-associated protein and mediates Ca(2+)-calmodulin modulation.''; PubMed Europe PMC Scholia
  57. Ross D, Joyner WL.; ''Resting distribution and stimulated translocation of protein kinase C isoforms alpha, epsilon and zeta in response to bradykinin and TNF in human endothelial cells.''; PubMed Europe PMC Scholia
  58. Coleman DE, Berghuis AM, Lee E, Linder ME, Gilman AG, Sprang SR.; ''Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis.''; PubMed Europe PMC Scholia
  59. Johnson EA, Oldfield S, Braksator E, Gonzalez-Cuello A, Couch D, Hall KJ, Mundell SJ, Bailey CP, Kelly E, Henderson G.; ''Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells.''; PubMed Europe PMC Scholia
  60. Burford NT, Tolbert LM, Sadee W.; ''Specific G protein activation and mu-opioid receptor internalization caused by morphine, DAMGO and endomorphin I.''; PubMed Europe PMC Scholia
  61. Simpson RE, Ciruela A, Cooper DM.; ''The role of calmodulin recruitment in Ca2+ stimulation of adenylyl cyclase type 8.''; PubMed Europe PMC Scholia
  62. Clark MJ, Traynor JR.; ''Mediation of adenylyl cyclase sensitization by PTX-insensitive GalphaoA, Galphai1, Galphai2 or Galphai3.''; PubMed Europe PMC Scholia
  63. Gaibelet G, Meilhoc E, Riond J, Saves I, Exner T, Liaubet L, Nürnberg B, Masson JM, Emorine LJ.; ''Nonselective coupling of the human mu-opioid receptor to multiple inhibitory G-protein isoforms.''; PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
116415view09:08, 7 May 2021EweitzModified title
115086view17:03, 25 January 2021ReactomeTeamReactome version 75
113528view12:00, 2 November 2020ReactomeTeamReactome version 74
112726view16:12, 9 October 2020ReactomeTeamReactome version 73
101642view11:50, 1 November 2018ReactomeTeamreactome version 66
101178view21:37, 31 October 2018ReactomeTeamreactome version 65
100704view20:10, 31 October 2018ReactomeTeamreactome version 64
100254view16:55, 31 October 2018ReactomeTeamreactome version 63
99807view15:20, 31 October 2018ReactomeTeamreactome version 62 (2nd attempt)
99353view12:48, 31 October 2018ReactomeTeamreactome version 62
93848view13:40, 16 August 2017ReactomeTeamreactome version 61
93406view11:22, 9 August 2017ReactomeTeamreactome version 61
88062view14:04, 25 July 2016RyanmillerOntology Term : 'chemical compound signaling pathway' added !
88061view14:04, 25 July 2016RyanmillerOntology Term : 'signaling pathway' added !
86494view09:19, 11 July 2016ReactomeTeamreactome version 56
83304view10:42, 18 November 2015ReactomeTeamVersion54
81440view12:58, 21 August 2015ReactomeTeamVersion53
76919view08:19, 17 July 2014ReactomeTeamFixed remaining interactions
76624view11:59, 16 July 2014ReactomeTeamFixed remaining interactions
75955view10:01, 11 June 2014ReactomeTeamRe-fixing comment source
75657view10:55, 10 June 2014ReactomeTeamReactome 48 Update
75012view13:52, 8 May 2014AnweshaFixing comment source for displaying WikiPathways description
74656view08:43, 30 April 2014ReactomeTeamReactome46
56299view16:38, 5 January 2013EgonwData typed a ChEBI metabolite as such.
42186view23:51, 4 March 2011MaintBotModified categories
42185view23:51, 4 March 2011MaintBot
42184view23:50, 4 March 2011MaintBotNew pathway

External references

DataNodes

No datanodes

Annotated Interactions

No annotated interactions

Retrieved from "https://oldclassic.wikipathways.org/index.php/Pathway:WP1978"
Personal tools