Histidine metabolism (Mycobacterium tuberculosis)

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Pentose phosphate pathwayAlanine, aspartate and glutamate metabolismPurine metabolismAlanine, aspartate and glutamate metabolismL-HistidineHercynineIsoglutamineFormylisoglutamineHistamineko:K012705-Aminoimidazole-4-carboxamide ribotideD-erythro-Imidazole-glycerol phosphateN-MethylhistamineMethylimidazoleacetic acidko:K00546cpd:C01100hisC2Imidazole-acetol phosphateko:K01593ko:K05604cpd:C05570hisAhisEPhosphoribulosyl-formimino-AICAR-phosphateec:3.4.13.54-Imidazolone-5-acetate4-(beta-Acetylaminoethyl)imidazoleko:K00603ec:1.14.13.5ec:2.6.1.384-Imidazolone-5-propanoatecpd:C00860Hydantoin-5-propionateec:3.5.3.5ko:K01468ec:3.5.2.-4-OxoglutaramatealdAko:K00129Imidazole lactateec:3.5.1.8putative methyltransferase (EC:2.1.1.-)cpd:C01044hisFcpd:C01045ec:6.3.2.11ko:K01458AnserinehisGhisB2-OxoglutarateL-Aspartatealdehyde dehydrogenase (EC:1.2.1.-)ec:6.3.4.8CarnosinealdCPhosphoribosyl-formimino-AICAR-phosphateko:K01479Phosphoribosyl-AMPMethylimidazole acetaldehydeko:K01437ko:K01089N-Formimino-L-aspartatealdehyde dehydrogenase (EC:1.2.1.3)aofH5-Phosphoribosyl diphosphateko:K04486hisDcpd:C05571ec:2.1.1.22Imidazole-4-acetateko:K11182cpd:C04437Urocanateko:K01712cpd:C05829Imidazole-4-acetaldehydemonooxygenase (EC:1.14.-.-)ko:K05602ko:K05603N-Formimino-L-glutamateN(pi)-Methyl-L-histidinecpd:C01929hisIcpd:C05131hisC1ko:K01590ec:6.3.2.11hisHPhosphoribosyl-ATPec:2.3.1.-hisDko:K01745Imidazol-5-yl-pyruvateL-Glutamate


Description

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
137608view17:57, 5 March 2025KhanspersModified description
134124view23:10, 28 June 2024Khanspersupdate board height
115241view08:29, 7 February 2021EgonwMade one more pathway clickable
101920view13:15, 17 November 2018EgonwReplaced old Uniprot data sources with the new ones.
95555view13:44, 27 December 2017DeSlRemoved licence number
95427view16:25, 14 December 2017DeSlOntology Term : 'Mycobacterium tuberculosis infection pathway' added !
95426view16:24, 14 December 2017DeSlModified description
95425view16:23, 14 December 2017DeSlModified description
95424view16:19, 14 December 2017DeSlRemoved all faulty IDs (KEGG orthologs), exchanged with ECnumbers. Added missing metabolites, removed the ones which could not be present biologically. Changed layout. Changged arrows to correct MIM type. Connected all enzymes accordingly.
77717view17:05, 15 October 2014EgonwReplaced 'Kegg enzyme' (not in recent BridgeDb versions) with 'Enzyme Nomenclature'.
72095view21:36, 24 October 2013Mkutmonadded datasource for "Purin metabolism"
71650view19:34, 17 October 2013MaintBotAutomated update of data sources
69571view20:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
67338view10:39, 26 June 2013Christine ChichesterOntology Term : 'histidine metabolic pathway' added !
41507view01:12, 2 March 2011MaintBotRemoved redundant pathway information and comments
40071view03:27, 6 February 2011AlexanderPicocurated edges
38996view19:41, 25 September 2010AlexanderPicoModified description
38995view19:41, 25 September 2010AlexanderPico
38994view19:40, 25 September 2010AlexanderPicofixed lines, groups and pathway nodes; refactored layout a bit
38630view21:06, 22 September 2010AllanKuchinskymoved EC:2.1.1.- to a straight line
38613view00:52, 22 September 2010AllanKuchinskyremoved spurious enzyme family -- ajk
38212view23:25, 26 August 2010KhanspersChanged xrefs
38211view23:08, 26 August 2010KhanspersChanged xrefs
37736view21:35, 29 June 2010KhanspersModified categories
37735view19:18, 29 June 2010KhanspersRemoved group
37734view19:16, 29 June 2010KhanspersNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2-OxoglutarateMetaboliteC00026 (Kegg Compound)
4-(beta-Acetylaminoethyl)imidazoleMetaboliteC05135 (Kegg Compound)
4-Imidazolone-5-acetateMetaboliteC05133 (Kegg Compound)
4-Imidazolone-5-propanoateMetaboliteC03680 (Kegg Compound)
4-OxoglutaramateMetaboliteC05572 (Kegg Compound)
5-Aminoimidazole-4-carboxamide ribotideMetaboliteC04677 (Kegg Compound)
5-Phosphoribosyl diphosphateMetaboliteC00119 (Kegg Compound)
AnserineMetaboliteC01262 (Kegg Compound)
CarnosineMetaboliteC00386 (Kegg Compound)
D-erythro-Imidazole-glycerol phosphateMetaboliteC04666 (Kegg Compound)
FormylisoglutamineMetaboliteC16674 (Kegg Compound)
HercynineMetaboliteC05575 (Kegg Compound)
HistamineMetaboliteC00388 (Kegg Compound)
Hydantoin-5-propionateMetaboliteC05565 (Kegg Compound)
Imidazol-5-yl-pyruvateMetaboliteC03277 (Kegg Compound)
Imidazole lactateMetaboliteC05568 (Kegg Compound)
Imidazole-4-acetaldehydeMetaboliteC05130 (Kegg Compound)
Imidazole-4-acetateMetaboliteC02835 (Kegg Compound)
Imidazole-acetol phosphateMetaboliteC01267 (Kegg Compound)
IsoglutamineMetaboliteC16673 (Kegg Compound)
L-AspartateMetaboliteC00049 (Kegg Compound)
L-GlutamateMetaboliteC00025 (Kegg Compound)
L-HistidineMetaboliteC00135 (Kegg Compound)
Methylimidazole acetaldehydeMetaboliteC05827 (Kegg Compound)
Methylimidazoleacetic acidMetaboliteC05828 (Kegg Compound)
N(pi)-Methyl-L-histidineMetaboliteC01152 (Kegg Compound)
N-Formimino-L-aspartateMetaboliteC03409 (Kegg Compound)
N-Formimino-L-glutamateMetaboliteC00439 (Kegg Compound)
N-MethylhistamineMetaboliteC05127 (Kegg Compound)
Phosphoribosyl-AMPMetaboliteC02741 (Kegg Compound)
Phosphoribosyl-ATPMetaboliteC02739 (Kegg Compound)
Phosphoribosyl-formimino-AICAR-phosphateMetaboliteC04896 (Kegg Compound)
Phosphoribulosyl-formimino-AICAR-phosphateMetaboliteC04916 (Kegg Compound)
UrocanateMetaboliteC00785 (Kegg Compound)
aldAGeneProductRv0768 (TubercuList) Original kegg element: gene;19;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldCGeneProductRv2858c (TubercuList) Original kegg element: gene;19;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldehyde dehydrogenase (EC:1.2.1.-)GeneProductRv0147 (TubercuList) Original kegg element: gene;19;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aldehyde dehydrogenase (EC:1.2.1.3)GeneProductRv0458 (TubercuList) Original kegg element: gene;19;mtu:Rv0147 mtu:Rv0458 mtu:Rv0768 mtu:Rv2858c
aofHGeneProductRv3170 (TubercuList) Original kegg element: gene;20;mtu:Rv3170
cpd:C00860MetaboliteC00860 (Kegg Compound)
cpd:C01044MetaboliteC01044 (Kegg Compound)
cpd:C01045MetaboliteC01045 (Kegg Compound)
cpd:C01100MetaboliteC01100 (Kegg Compound)
cpd:C01929MetaboliteC01929 (Kegg Compound)
cpd:C04437MetaboliteC04437 (Kegg Compound)
cpd:C05131MetaboliteC05131 (Kegg Compound)
cpd:C05570MetaboliteC05570 (Kegg Compound)
cpd:C05571MetaboliteC05571 (Kegg Compound)
cpd:C05829MetaboliteC05829 (Kegg Compound)
ec:1.14.13.5GeneProduct1.14.13.5 (Kegg enzyme)
ec:2.1.1.22GeneProduct2.1.1.22 (Kegg enzyme)
ec:2.3.1.-GeneProduct2.3.1.- (Kegg enzyme)
ec:2.6.1.38GeneProduct2.6.1.38 (Kegg enzyme)
ec:3.4.13.5GeneProduct3.4.13.5 (Kegg enzyme)
ec:3.5.1.8GeneProduct3.5.1.8 (Kegg enzyme)
ec:3.5.2.-GeneProduct3.5.2.- (Kegg enzyme)
ec:3.5.3.5GeneProduct3.5.3.5 (Kegg enzyme)
ec:6.3.2.11GeneProduct6.3.2.11 (Kegg enzyme)
ec:6.3.4.8GeneProduct6.3.4.8 (Kegg enzyme)
hisAGeneProductRv1603 (TubercuList) Original kegg element: gene;32;mtu:Rv1603
hisBGeneProductRv1601 (TubercuList) Original kegg element: gene;30;mtu:Rv1601
hisC1GeneProductRv1600 (TubercuList) Original kegg element: gene;29;mtu:Rv1600 mtu:Rv3772
hisC2GeneProductRv3772 (TubercuList) Original kegg element: gene;29;mtu:Rv1600 mtu:Rv3772
hisDGeneProductRv1599 (TubercuList) Original kegg element: gene;26;mtu:Rv1599
hisEGeneProductRv2122c (TubercuList) Original kegg element: gene;34;mtu:Rv2122c
hisFGeneProductRv1605 (TubercuList) Original kegg element: gene;36;mtu:Rv1605
hisGGeneProductRv2121c (TubercuList) Original kegg element: gene;25;mtu:Rv2121c
hisHGeneProductRv1602 (TubercuList) Original kegg element: gene;91;mtu:Rv1602
hisIGeneProductRv1606 (TubercuList) Original kegg element: gene;33;mtu:Rv1606
ko:K00129GeneProductK00129 (Kegg ortholog)
ko:K00546GeneProductK00546 (Kegg ortholog)
ko:K00603GeneProductK00603 (Kegg ortholog)
ko:K01089GeneProductK01089... (Kegg ortholog)
ko:K01270GeneProductK01270 (Kegg ortholog)
ko:K01437GeneProductK01437 (Kegg ortholog)
ko:K01458GeneProductK01458 (Kegg ortholog)
ko:K01468GeneProductK01468 (Kegg ortholog)
ko:K01479GeneProductK01479 (Kegg ortholog)
ko:K01590GeneProductK01590 (Kegg ortholog)
ko:K01593GeneProductK01593 (Kegg ortholog)
ko:K01712GeneProductK01712 (Kegg ortholog)
ko:K01745GeneProductK01745 (Kegg ortholog)
ko:K04486GeneProductK01089... (Kegg ortholog)
ko:K05602GeneProductK01089... (Kegg ortholog)
ko:K05603GeneProductK05603 (Kegg ortholog)
ko:K05604GeneProductK05604 (Kegg ortholog)
ko:K11182GeneProductK11182 (Kegg ortholog)
monooxygenase (EC:1.14.-.-)GeneProductRv0892 (TubercuList) Original kegg element: gene;2;mtu:Rv0892
putative methyltransferase (EC:2.1.1.-)GeneProduct

Annotated Interactions

No annotated interactions

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