Ubiquinone biosynthesis (Saccharomyces cerevisiae)

Quality Tags

Ontology Terms

Saving...

Bibliography

1. Tran UC, Clarke CF; ''Endogenous synthesis of coenzyme Q in eukaryotes.''; Mitochondrion, 2007 PubMed Europe PMC Scholia
2. Meganathan R; ''Ubiquinone biosynthesis in microorganisms.''; FEMS Microbiol Lett, 2001 PubMed Europe PMC Scholia
3. Marbois B, Gin P, Faull KF, Poon WW, Lee PT, Strahan J, Shepherd JN, Clarke CF; ''Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
4. Baba SW, Belogrudov GI, Lee JC, Lee PT, Strahan J, Shepherd JN, Clarke CF; ''Yeast Coq5 C-methyltransferase is required for stability of other polypeptides involved in coenzyme Q biosynthesis.''; J Biol Chem, 2004 PubMed Europe PMC Scholia
5. Lobo Z, Maitra PK; ''Genetics of Yeast Hexokinase.''; Genetics, 1977 PubMed Europe PMC Scholia
6. Belogrudov GI, Lee PT, Jonassen T, Hsu AY, Gin P, Clarke CF; ''Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesis.''; Arch Biochem Biophys, 2001 PubMed Europe PMC Scholia
7. Jonassen T, Proft M, Randez-Gil F, Schultz JR, Marbois BN, Entian KD, Clarke CF; ''Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis.''; J Biol Chem, 1998 PubMed Europe PMC Scholia
8. SUGIMURA T, RUDNEY H; ''The adaptive formation of ubiquinone 30 (coenzyme Q6) in yeast.''; Biochim Biophys Acta, 1960 PubMed Europe PMC Scholia
9. Tran UC, Marbois B, Gin P, Gulmezian M, Jonassen T, Clarke CF; ''Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis.''; J Biol Chem, 2006 PubMed Europe PMC Scholia
10. Ashby MN, Edwards PA; ''Elucidation of the deficiency in two yeast coenzyme Q mutants. Characterization of the structural gene encoding hexaprenyl pyrophosphate synthetase.''; J Biol Chem, 1990 PubMed Europe PMC Scholia
11. Hsu AY, Poon WW, Shepherd JA, Myles DC, Clarke CF; ''Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis.''; Biochemistry, 1996 PubMed Europe PMC Scholia
12. Gin P, Clarke CF; ''Genetic evidence for a multi-subunit complex in coenzyme Q biosynthesis in yeast and the role of the Coq1 hexaprenyl diphosphate synthase.''; J Biol Chem, 2005 PubMed Europe PMC Scholia
13. Olson RE, Rudney H; ''Biosynthesis of ubiquinone.''; Vitam Horm, 1983 PubMed Europe PMC Scholia
14. Casey J, Threlfall DR; ''Synthesis of 5-demethoxyubiquinone-6 and ubiquinone-6 from 3-hexaprenyl-4-hydroxybenzoate in yeast mitochondria.''; FEBS Lett, 1978 PubMed Europe PMC Scholia
15. Hsieh EJ, Gin P, Gulmezian M, Tran UC, Saiki R, Marbois BN, Clarke CF; ''Saccharomyces cerevisiae Coq9 polypeptide is a subunit of the mitochondrial coenzyme Q biosynthetic complex.''; Arch Biochem Biophys, 2007 PubMed Europe PMC Scholia
16. Dibrov E, Robinson KM, Lemire BD; ''The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain.''; J Biol Chem, 1997 PubMed Europe PMC Scholia

History

External references

DataNodes

Name	Type	Database reference	Comment
ATP		1927-31-7 (CAS)
BTS1	GeneProduct	S000005990 (SGD)
CAT5	GeneProduct	S000005651 (SGD)
COQ1	GeneProduct	S000000207 (SGD)
COQ2	GeneProduct	S000005324 (SGD)
COQ3	GeneProduct	S000005456 (SGD)
COQ5	GeneProduct	S000004578 (SGD)
COQ6	GeneProduct	S000003487 (SGD)
Coenzyme A		64885-97-8 (CAS)
ERG20	GeneProduct	S000003703 (SGD)
L-tyrosine		60-18-4 (CAS)
NADH		53-84-9 (CAS)
acetyl-CoA		72-89-9 (CAS)
chorismate		55508-12-8 (CAS)
geranylgeranyl-PP		6699-20-3 (CAS)
pyrophosphate		2466-09-3 (CAS)

Annotated Interactions