Docosahexaenoic acid oxylipin metabolism (Homo sapiens)

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Description

Docosahexaenoic acid (DHA) oxylipin metabolism, involving the LOX, COX2, and sEH genes.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Wang CW, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE, Serhan CN; ''Maresin 1 Biosynthesis and Proresolving Anti-infective Functionswith Human-Localized Aggressive Periodontitis Leukocytes.''; Infect Immun, 2015 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
142562view09:21, 22 March 2026EgonwAdded a missing identifier
142561view09:18, 22 March 2026EgonwModified description
141431view11:47, 14 November 2025DeSlConnected all unconnected lines
141381view13:39, 11 November 2025EweitzStandardize case
141380view13:36, 11 November 2025EweitzEconomize layout
141363view03:52, 11 November 2025EweitzClear cached dimensions
141362view03:51, 11 November 2025EweitzEconomize layout
134710view12:22, 26 July 2024EweitzOntology Term : 'fatty acid metabolic pathway' added !
123805view11:43, 16 August 2022EgonwResolvin D6 had the HMDB identifier for D5 so replaced it with the ChEBI identifier for D6
123623view08:24, 7 August 2022EgonwModified title
122424view22:30, 1 April 2022AlexanderPicoOntology Term : 'classic metabolic pathway' added !
121501view20:55, 18 February 2022Lcayer17-oxo-DoHE selected instead of 7-
120861view21:38, 20 January 2022LcayerFixed position of Maresin 1&2. Their precursor is 14-HpDoHE.
120632view21:04, 21 December 2021LcayerOntology Term : 'lipid metabolic pathway' added !
120631view21:04, 21 December 2021LcayerModified title
120627view17:09, 21 December 2021LcayerNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
10(11)-EpDPEMetaboliteCHEBI:136569 (ChEBI)
10,11-DiHDPEMetabolite16061145 (PubChem-compound)
10-HDoHEMetaboliteHMDB60037 (HMDB)
10-HpDoHEMetabolite
11-HDoHEMetaboliteHMDB60040 (HMDB)
11-HpDoHEMetabolite
13(14)-EpDPEMetaboliteCHEBI:136563 (ChEBI)
13,14-DiHDPEMetabolite87204854 (PubChem-compound)
13-HDoHEMetaboliteCHEBI:72608 (ChEBI)
13-HpDoHEMetabolite
14,20-DiHDoHEMetabolite
14,21-DiHDoHEMetabolite
14-HDoHEMetaboliteHMDB60044 (HMDB)
14-HpDoHEMetabolite
16(17)-EpDPEMetaboliteCHEBI:72855 (ChEBI)
16,17-DiHDPEMetabolite16061147 (PubChem-compound)
16-HDoHEMetaboliteHMDB60047 (HMDB)
16-HpDoHEMetabolite
17(R)-HpDoHEMetaboliteCHEBI:138590 (ChEBI)
17-HDoHEMetaboliteCHEBI:72637 (ChEBI)
17-HpDoHEMetabolite
19(20)-EpDPEMetaboliteCHEBI:72653 (ChEBI)
19,20-DiHDPEMetabolite16061148 (PubChem-compound)
20-HDoHEMetaboliteHMDB60048 (HMDB)
21-HDoHEMetaboliteQ27225538 (Wikidata)
22-HDoHEMetaboliteCHEBI:77124 (ChEBI)
4(5)-EpDPEMetabolite
4,5-DiHDPEMetabolite14429107 (PubChem-compound)
4-HDoHEMetaboliteHMDB60049 (HMDB)
4-HpDoHEMetabolite
7(8)-EpDPEMetabolite11653103 (PubChem-compound)
7,8-DiHDPEMetabolite16061144 (PubChem-compound)
7-HDoHEMetaboliteCHEBI:72623 (ChEBI)
7-HpDoHEMetabolite
7-oxo-DoHEMetabolite
8-HDoHEMetaboliteHMDB60051 (HMDB)
8-HpDoHEMetabolite
ASAMetaboliteCHEBI:15365 (ChEBI)
Aspirin-triggered protectin D1MetaboliteQ60998647 (Wikidata)
Aspirin-triggered resolvin D1MetaboliteCHEBI:138179 (ChEBI)
Aspirin-triggered resolvin D2MetaboliteCHEBI:138614 (ChEBI)
Aspirin-triggered resolvin D3MetaboliteCHEBI:138615 (ChEBI)
Aspirin-triggered resolvin D4MetaboliteCHEBI:138616 (ChEBI)
COX2GeneProductENSG00000073756 (Ensembl)
CYP epoxygenaseGeneProduct
CYP omega-hydrolaseGeneProduct
DHAMetaboliteCHEBI:36005 (ChEBI)
LOXGeneProduct
Maresin 1MetaboliteCHEBI:138249 (ChEBI)
Maresin 2MetaboliteCHEBI:138248 (ChEBI)
Neuroprotectin D1MetaboliteHMDB03689 (HMDB)
PDXMetaboliteCHEBI:138653 (ChEBI)
Protectin D1MetaboliteQ18345077 (Wikidata)
Resolvin D1MetaboliteCHEBI:132079 (ChEBI)
Resolvin D2MetaboliteHMDB02294 (HMDB)
Resolvin D3MetaboliteQ59864196 (Wikidata)
Resolvin D4MetaboliteQ59864198 (Wikidata)
Resolvin D5MetaboliteHMDB04038 (HMDB)
Resolvin D6Metabolite138643 (ChEBI)
sEHGeneProduct2053 (Entrez Gene)

Annotated Interactions

No annotated interactions

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