Vedolizumab therapy for inflammatory bowel disease (Homo sapiens)

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Description

"Process of lymphocyte migration from the blood vessels to the intestinal mucosa and mechanism of action of vedolizumab." Inspired by Figure 1 in https://pubmed.ncbi.nlm.nih.gov/31470005/.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Eugeni Domenecha, Javier P. Gisbert; ''Efficacy and safety of vedolizumab in the treatment of ulcerative colitis''; Gastroenterologia y Hepatologia, 2016

History

View all...
CompareRevisionActionTimeUserComment
140911view11:14, 30 October 2025EweitzClear deprecated metadata rendering
137069view03:02, 27 February 2025EweitzOntology Term : 'inflammatory bowel disease' added !
137068view03:01, 27 February 2025EweitzOntology Term : 'DOID:9778' removed !
137067view03:01, 27 February 2025EweitzModified title
136453view01:04, 3 February 2025EweitzShrink last nucleus
136452view01:03, 3 February 2025EweitzEconomize layout
136450view22:16, 2 February 2025EweitzRefine graphical X placement
136449view22:01, 2 February 2025EweitzRemove a rolling indicator due to curved line rendering bug
136448view22:00, 2 February 2025EweitzMitigate graphical bug due to PathVisio / Kaavio discrepancy
136447view21:59, 2 February 2025EweitzMitigate graphical bug due to PathVisio / Kaavio discrepancy
136446view21:58, 2 February 2025EweitzAdd, refine rolling indicator
136445view21:50, 2 February 2025EweitzOntology Term : 'ulcerative colitis' added !
136444view21:49, 2 February 2025EweitzOntology Term : 'Crohn's disease' added !
136443view21:47, 2 February 2025EweitzOntology Term : 'irritable bowel syndrome' added !
136442view21:47, 2 February 2025EweitzOntology Term : 'lymphocyte' added !
136441view21:46, 2 February 2025EweitzOntology Term : 'endothelial cell of vascular tree' added !
136440view21:46, 2 February 2025EweitzModified description
136439view21:43, 2 February 2025EweitzAdd literature reference
136438view21:41, 2 February 2025EweitzAbut endothelial cells
136437view21:39, 2 February 2025EweitzAdd familiar terms
136436view21:35, 2 February 2025EweitzModified description
136435view21:32, 2 February 2025EweitzLabel tissues
136434view21:28, 2 February 2025EweitzAdjust position of cell type label, nucleus
136433view21:25, 2 February 2025EweitzFix connection
136432view21:24, 2 February 2025EweitzRefine color, add interaction
136431view21:22, 2 February 2025EweitzRefine color
136430view21:20, 2 February 2025EweitzAdd color
136429view21:06, 2 February 2025EweitzAdd process phases, label cell types
136428view13:28, 2 February 2025EweitzRefine graphics
136427view13:27, 2 February 2025EweitzUpgrade to complexes, add interactions
136426view13:13, 2 February 2025EweitzNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ICAM1GeneProductENSG00000090339 (Ensembl)
ITGA2GeneProductENSG00000164171 (Ensembl)
ITGA4GeneProductENSG00000115232 (Ensembl)
ITGB1GeneProductENSG00000150093 (Ensembl)
ITGB2GeneProductENSG00000160255 (Ensembl)
ITGB7GeneProductENSG00000139626 (Ensembl)
MADCAM1GeneProductENSG00000099866 (Ensembl)
SELEGeneProductENSG00000007908 (Ensembl)
SELPLGGeneProductENSG00000110876 (Ensembl)
VCAM1GeneProductENSG00000162692 (Ensembl)
VedolizumabMetaboliteDB09033 (DrugBank)

Annotated Interactions

No annotated interactions

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