miR-517 relationship with ARCN1 and USP1 (Homo sapiens)
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Description
Schematic summarizing predicted miR-517a relationships with ARCN1 and USP1.
A genomewide miRNA mimic toxicity screen indicates common and selective vulnerabilities of epithelial ovarian cancer cells. miR-517a targets a common vulnerability, primarily via its target ARCN1.
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Ontology Terms
Bibliography
- Shields BB, Pecot CV, Gao H, McMillan E, Potts M, Nagel C, Purinton S, Wang Y, Ivan C, Kim HS, Borkowski RJ, Khan S, Rodriguez-Aguayo C, Lopez-Berestein G, Lea J, Gazdar A, Baggerly KA, Sood AK, White MA; ''A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression.''; Mol Syst Biol, 2015 PubMed Europe PMC Scholia
History
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External references
DataNodes
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| Name | Type | Database reference | Comment |
|---|---|---|---|
| ARCN1 | GeneProduct | ENSG00000095139 (Ensembl) ![]() | |
| ID1 | GeneProduct | ENSG00000125968 (Ensembl) ![]() | |
| ID2 | GeneProduct | ENSG00000115738 (Ensembl) ![]() | |
| USP1 | GeneProduct | ENSG00000162607 (Ensembl) ![]() | |
| hsa-miR-517a-3p | Rna | MIMAT0002852 (miRBase mature sequence) ![]() | |
| p21 | GeneProduct | ENSG00000124762 (Ensembl) ![]() |
Annotated Interactions
No annotated interactions
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