Apoptosis-related network due to altered Notch3 in ovarian cancer (Homo sapiens)

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1APOESERBP1TNFRSF10BERBB3TNFSQSTM1NET1CUL5RIPK2CUL1CDKN1AAKT1HSPB1CTNNA1HSPD1HELLSANXA5HDAC1NFKB1BCL3TRAF1NGFRAP1RNF7PTK2ETS1MAPK1CDKN1BRPS6KB1PPP2GBAXIN1SMAD7VIMPKN1IER3CSDACARD14NQO1GCLCJUNDF2RBIRC5THBS1TNFRSF21APPCASP7NRG1ABL1PAK2SOCS3IL7RPTK2BVAV3ERN1HSPA5


Description

Results of pathway analysis of apoptosis-related genes in OVCAR3 cells treated with Notch3 siRNA or control siRNA. This pathway is part the CPTAC Assay Portal.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK; ''Notch3 pathway alterations in ovarian cancer.''; Cancer Res, 2014 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
140956view22:49, 30 October 2025EweitzClear deprecated metadata rendering
137160view00:45, 28 February 2025KhanspersModified description
108133view10:30, 29 November 2019FehrhartOntology Term : 'cancer pathway' added !
106299view17:42, 20 August 2019KhanspersModified description
105531view06:02, 9 August 2019KhanspersModified description
79278view22:22, 19 March 2015ZariAdded Identifier for BCL3
77986view18:12, 4 November 2014KhanspersOntology Term : 'apoptotic cell death pathway' added !
77869view19:11, 23 October 2014KhanspersModified title
77856view21:04, 22 October 2014KhanspersOntology Term : 'reproductive organ cancer' added !
77776view18:21, 17 October 2014Khanspersadded lit ref
77775view18:16, 17 October 2014KhanspersModified description
77774view18:12, 17 October 2014KhanspersNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABL1GeneProduct25 (Entrez Gene)
AKT1GeneProduct207 (Entrez Gene)
ANXA5GeneProduct308 (Entrez Gene)
APOEGeneProduct348 (Entrez Gene)
APPGeneProduct351 (Entrez Gene)
AXIN1GeneProduct8312 (Entrez Gene)
BCL3Protein602 (Entrez Gene)
BIRC5GeneProduct332 (Entrez Gene)
CARD14GeneProduct79092 (Entrez Gene)
CASP7GeneProduct840 (Entrez Gene)
CDKN1AGeneProduct1026 (Entrez Gene)
CDKN1BGeneProduct1027 (Entrez Gene)
CSDAGeneProduct8531 (Entrez Gene)
CTNNA1GeneProduct1495 (Entrez Gene)
CUL1GeneProduct8454 (Entrez Gene)
CUL5GeneProduct8065 (Entrez Gene)
ERBB3GeneProduct2065 (Entrez Gene)
ERN1GeneProduct2081 (Entrez Gene)
ETS1GeneProduct2113 (Entrez Gene)
F2RGeneProduct2149 (Entrez Gene)
GCLCGeneProduct2729 (Entrez Gene)
HDAC1GeneProduct3065 (Entrez Gene)
HELLSGeneProduct3070 (Entrez Gene)
HSPA5GeneProduct3309 (Entrez Gene)
HSPB1GeneProduct3315 (Entrez Gene)
HSPD1GeneProduct3329 (Entrez Gene)
IER3GeneProduct8870 (Entrez Gene)
IL7RGeneProduct3575 (Entrez Gene)
JUNDGeneProduct3727 (Entrez Gene)
MAPK1GeneProduct5594 (Entrez Gene)
NET1GeneProduct10276 (Entrez Gene)
NFKB1GeneProduct4790 (Entrez Gene)
NGFRAP1GeneProduct27018 (Entrez Gene)
NQO1GeneProduct1728 (Entrez Gene)
NRG1GeneProduct3084 (Entrez Gene)
PAK2GeneProduct5062 (Entrez Gene)
PKN1GeneProduct5585 (Entrez Gene)
PPP2GBGeneProduct
PTK2GeneProduct5747 (Entrez Gene)
PTK2BGeneProduct2185 (Entrez Gene)
RIPK2GeneProduct8767 (Entrez Gene)
RNF7GeneProduct9616 (Entrez Gene)
RPS6KB1GeneProduct6198 (Entrez Gene)
SERBP1GeneProduct26135 (Entrez Gene)
SMAD7GeneProduct4092 (Entrez Gene)
SOCS3GeneProduct9021 (Entrez Gene)
SQSTM1GeneProduct8878 (Entrez Gene)
THBS1GeneProduct7057 (Entrez Gene)
TNFGeneProduct7124 (Entrez Gene)
TNFRSF10BGeneProduct8795 (Entrez Gene)
TNFRSF21GeneProduct27242 (Entrez Gene)
TRAF1GeneProduct7185 (Entrez Gene)
VAV3GeneProduct10451 (Entrez Gene)
VIMGeneProduct7431 (Entrez Gene)

Annotated Interactions

No annotated interactions

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