Drug induction of bile acid pathway (Homo sapiens)

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Revision as of 14:40, 28 August 2012 by Riannefijten (Talk | contribs)
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1HepatocyteSensingHepatic UptakeCholesterolCyclosporinOSTalphaTroglitazoneSLCO1B1EzetimibeBA-RBAATChlorpromazineTetrahydrocortisoneCYP7A1CYP3A4Bile AcidsSLC10A1ABCB1Glycocholic acidClozapineSULT2A1NR1H4MetabolitesBileBile DuctTaurocholic acidBilirubinIsoursodeoxycholic acidDeoxycholic acidVDRNR1I3NR1I2MethylprednisoloneCimetidineOSTBETAABCC4ABCB11ABCC3ABCC2PhospholipidsDigoxinClarithromyciErythromycinSilybinGlyburideTacrolimusTrabectedinPhominColchicineRanitidineOxiglutationeSynthesisConjugationSecretion


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. NGP E-Magazine; ''Mechanistic Disease Modeling''; http://www.ngpharma.com/article/Mechanistic-Disease-Modeling/, 2012

History

View all...
CompareRevisionActionTimeUserComment
141430view11:44, 14 November 2025DeSlAdded missing ID for BA-R (assumed to be Bile-acid with any sidechain
141368view03:56, 11 November 2025EweitzClear deprecated metadata rendering
128660view04:11, 18 February 2024EweitzOntology Term : 'hepatocyte' added !
128659view04:04, 18 February 2024EweitzUse gene symbols, economize layout
120498view07:29, 9 December 2021EgonwReplaced an old PubChem CID with the new one
117705view12:26, 22 May 2021EweitzModified title
106211view12:10, 16 August 2019MaintBotHMDB identifier normalization
97831view06:27, 10 June 2018EgonwModified description
97745view13:07, 7 June 2018RoelodModified description
97743view13:05, 7 June 2018RoelodModified description
88593view19:40, 11 August 2016Mkutmonfix unconnected lines
87242view09:57, 20 July 2016SusanOntology Term : 'bile acid signaling pathway' added !
87241view09:56, 20 July 2016SusanOntology Term : 'drug pathway' added !
78511view10:29, 7 January 2015MaintBotadded missing graphIds
70504view11:46, 8 August 2013EgonwAdded a ChEBI id for the phospholipid compound class.
68912view17:31, 8 July 2013MaintBotUpdated to 2013 gpml schema
60232view21:49, 14 March 2013EgonwAdded a reference to ChEBI for 'bile acid'.
57150view12:35, 23 January 2013EgonwUsed "PubChem-compound"
53119view01:34, 30 October 2012MaintBotModified categories
51078view14:40, 28 August 2012RiannefijtenAdded reference on which the pathway is based
51077view14:32, 28 August 2012RiannefijtenNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABCB11GeneProduct8647 (Entrez Gene)
ABCB1GeneProduct5243 (Entrez Gene)
ABCC2GeneProduct1244 (Entrez Gene)
ABCC3GeneProduct8714 (Entrez Gene)
ABCC4GeneProduct10257 (Entrez Gene)
BA-RMetabolite
BAATGeneProduct570 (Entrez Gene)
Bile Acids Metabolite
BilirubinMetaboliteHMDB00054 (HMDB)
CYP3A4GeneProduct1576 (Entrez Gene)
CYP7A1GeneProduct1581 (Entrez Gene)
ChlorpromazineMetabolite2726 (PubChem)
CholesterolMetaboliteHMDB00067 (HMDB)
CimetidineMetabolite2756 (PubChem)
ClarithromyciMetabolite84029 (PubChem)
Clozapine Metabolite2818 (PubChem)
Colchicine Metabolite6167 (PubChem)
Cyclosporin Metabolite5284373 (PubChem)
Deoxycholic acidMetaboliteHMDB00626 (HMDB)
DigoxinMetaboliteHMDB01917 (HMDB)
ErythromycinMetabolite12560 (PubChem)
Ezetimibe Metabolite150311 (PubChem)
GlyburideMetabolite3488 (PubChem)
Glycocholic acidMetaboliteHMDB00138 (HMDB)
Isoursodeoxycholic acidMetaboliteHMDB00686 (HMDB)
MethylprednisoloneMetabolite6741 (PubChem)
NR1H4GeneProduct9971 (Entrez Gene)
NR1I2GeneProduct8856 (Entrez Gene)
NR1I3GeneProduct9970 (Entrez Gene)
OSTBETAGeneProduct123264 (Entrez Gene)
OSTalphaGeneProduct200931 (Entrez Gene)
OxiglutationeMetabolite65359 (PubChem)
Phomin Metabolite5311281 (PubChem)
PhospholipidsMetabolite
RanitidineMetaboliteHMDB01930 (HMDB)
SLC10A1GeneProduct6554 (Entrez Gene)
SLCO1B1GeneProduct10599 (Entrez Gene)
SULT2A1GeneProduct6822 (Entrez Gene)
SilybinMetabolite31553 (PubChem)
TacrolimusMetabolite445643 (PubChem)
Taurocholic acidMetaboliteHMDB00036 (HMDB)
TetrahydrocortisoneMetaboliteHMDB00903 (HMDB)
Trabectedin Metabolite108150 (PubChem)
TroglitazoneMetabolite5591 (PubChem)
VDRGeneProduct7421 (Entrez Gene)

Annotated Interactions

No annotated interactions

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