Nifedipine activity (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Hirata A, Igarashi M, Yamaguchi H, Suwabe A, Daimon M, Kato T, Tominaga M; ''Nifedipine suppresses neointimal thickening by its inhibitory effect on vascular smooth muscle cell growth via a MEK-ERK pathway coupling with Pyk2.''; Br J Pharmacol, 2000 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	140219	view	10:30, 7 August 2025	Egonw	Modified description
	126432	view	10:11, 28 April 2023	Egonw	License is CCZero
	118184	view	10:51, 25 May 2021	Eweitz	Modified title
	106191	view	12:08, 16 August 2019	MaintBot	HMDB identifier normalization
	88585	view	19:25, 11 August 2016	Mkutmon	fix unconnected lines
	75227	view	19:24, 12 May 2014	Khanspers	layout, xrefs, connections
	74419	view	12:42, 18 April 2014	Egonw	Converted two labels into metabolite DataNodes with an identifier.
	71991	view	11:18, 24 October 2013	Mkutmon	Changed Unknown -> GeneProduct for all annotated data nodes
	68905	view	17:30, 8 July 2013	MaintBot	Updated to 2013 gpml schema
	67508	view	11:18, 26 June 2013	Ddigles	Ontology Term : 'nifedipine drug pathway' added !
	45358	view	20:43, 7 October 2011	Khanspers	Modified description
	45357	view	20:42, 7 October 2011	Khanspers	Modified description
	45356	view	20:41, 7 October 2011	Khanspers	Ontology Term : 'heart disease' added !
	45355	view	20:40, 7 October 2011	Khanspers	Ontology Term : 'hypertension' added !
	41054	view	23:17, 1 March 2011	MaintBot	Removed redundant pathway information and comments
	39776	view	21:35, 17 January 2011	AlexanderPico	more complete title
	38868	view	18:23, 24 September 2010	Khanspers	Changed line types
	34583	view	22:23, 21 December 2009	Khanspers	Modified categories
	34447	view	18:20, 10 December 2009	MaintBot	Automatic update of empty xrefs
	26597	view	19:11, 10 December 2008	AlexanderPico	update
	26595	view	19:10, 10 December 2008	AlexanderPico	added connectors, database refs and literature ref
	26593	view	19:05, 10 December 2008	AlexanderPico	Periodical save, work in progress
	21223	view	11:31, 14 November 2008	MaintBot	[[Pathway:Homo sapiens:test1234]] moved to [[Pathway:WP259]]: Moved to stable identifier
	20471	view	10:39, 7 November 2008	Robatwiki	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
CYP2C11
CYP3A4		1576 (Entrez Gene)
Cholesterol esterase
Cholesterol hydrolase
MAP2K1		5604 (Entrez Gene)
MAPK1		5594 (Entrez Gene)
NADPH oxidase
PCNA		5111 (Entrez Gene)
PKC		50818 (Entrez Gene)
PTK2B		2185 (Entrez Gene)
SOD
VEGF

Annotated Interactions

No annotated interactions