Endothelin pathways (Bos taurus)

From WikiPathways

Revision as of 06:42, 19 July 2024 by Egonw (Talk | contribs)
Jump to: navigation, search


Description

Endothelin-1 is a bicyclic 21 amino acid peptide, produced primarily in the endothelium. It is a potent stimulus of long-lasting and persistent vasoconstriction. It also has a role as a stimulus of inflammation, oxidative stress and cellular proliferation.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2197(74852) with a 79.0% conversion rate.

Please use the New WikiPathways

View approved pathways at the new wikipathways.org. This website will shutdown soon.

Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
140185view05:46, 5 August 2025EgonwMore unicode
140009view05:47, 18 July 2025EgonwCalcium ion with unicode
134267view06:42, 19 July 2024EgonwRemoved template comments
117509view11:05, 21 May 2021EweitzModified title
105984view11:51, 16 August 2019MaintBotHMDB identifier normalization
80875view15:29, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADCY10GeneProductENSBTAG00000001052 (Ensembl)
  • adenylate cyclase
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000143199
ADRA1AGeneProductENSBTAG00000031632 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000120907
ADRB1GeneProductENSBTAG00000001242 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000043591
ATP2A2GeneProductENSBTAG00000001398 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000174437
ATPMetaboliteHMDB0001532 (HMDB)
Arachidonic acidMetaboliteHMDB0001043 (HMDB)
Big ET1Protein
CADGeneProductENSBTAG00000017894 (Ensembl)
  • Calmodulin binding protein; tonically inhibits the ATPase activity of myosin in smoothe muscle; mediating factor for Ca2+ dependent inhibition of smooth muscle contraction
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000084774
CALCRLGeneProductENSBTAG00000008483 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000064989
CNN1GeneProductENSBTAG00000011207 (Ensembl)
  • Calponin; tonically inhibits the ATPase activity of myosin in smooth muscle
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000130176
COIIGeneProductENSBTAG00000043556 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = L:4513
CTGeneProductENSBTAG00000047380 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000110680
CaMGeneProduct
Ca²⁺ channelGeneProduct
Ca²⁺MetaboliteHMDB0000464 (HMDB)
CitrullineMetaboliteHMDB0000904 (HMDB)
DAGMetaboliteHMDB0007008 (HMDB)
ECE1GeneProductENSBTAG00000002977 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000117298
EDHFProtein
EDN1GeneProductENSBTAG00000008096 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000078401
EDNRAGeneProductENSBTAG00000013674 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000151617
EDNRBGeneProductENSBTAG00000005299 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000136160
Furin-like proteaseProtein
GNA15GeneProductENSBTAG00000019988 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000060558
GNAI1GeneProductENSBTAG00000002714 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000127955
GNASGeneProductENSBTAG00000017475 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000087460
GNB5GeneProductENSBTAG00000003762 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000069966
GNG13GeneProductENSBTAG00000033526 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000127588
GTPMetaboliteHMDB0001440 (HMDB)
IP3MetaboliteHMDB0001059 (HMDB)
IP3RProtein
K+ channelProtein
K+MetaboliteHMDB0000586 (HMDB)
L-ArginineMetaboliteHMDB0000517 (HMDB)
MAP2K1GeneProductENSBTAG00000033983 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000169032
MAPK1GeneProductENSBTAG00000010312 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000100030
MYL1GeneProductENSBTAG00000009707 (Ensembl)
  • myosine light chain
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000168530
MYLKGeneProductENSBTAG00000014567 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000065534
NOMetaboliteHMDB0003378 (HMDB)
NOS3GeneProductENSBTAG00000017680 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000164867
NPY1RGeneProductENSBTAG00000047586 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000164128
NPYGeneProductENSBTAG00000004503 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000122585
PGI2Metabolite
PIP2MetaboliteHMDB0010032 (HMDB)
PLCB1GeneProductENSBTAG00000008338 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000182621
PMCAProtein
PRKCAGeneProductENSBTAG00000001061 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000154229
PTGIRGeneProductENSBTAG00000014585 (Ensembl)
  • Prostaglandin I2 Receptor
  • HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000160013
Pre-pro ET1Protein
RAF1GeneProductENSBTAG00000045748 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000132155
RAMP1GeneProductENSBTAG00000011534 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000132329
RIIAD1GeneProductENSBTAG00000032733 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000178796
cAMPMetaboliteHMDB0000058 (HMDB)
cGMPMetaboliteHMDB0001314 (HMDB)
sGCGeneProduct

Annotated Interactions

No annotated interactions
Retrieved from "https://oldclassic.wikipathways.org/index.php/Pathway:WP3246"
Personal tools