Non-classical role of vitamin D (Homo sapiens)

From WikiPathways

Revision as of 10:55, 30 September 2021 by Susan (Talk | contribs)
Jump to: navigation, search
1SSkinHTN & CVDLiverDiabetesSARS Cov-2 with genomeSARS glycoprotein spikeUV (295-320 nm)& anti-proliferationStrongImmunityIncrease in Na, K retention, Increase vasoconstrictionBlood streamKidneyReninInflammationApoptosisACEvitamin D receptor agonistscytokines and inflammationAngiotensinogenaldosteroneFibrosis1,25-dihydroxycholecalciferolAngiotensin II25-hydroxycholecalciferolVasodilationangiotensin I1-alpha-hydroxylase 7-DehydrocholesterolRenal Type-1 angiotensin II receptorACE2Cholecalciferol25-hydroxylase1,25-dihydroxycholecalciferolType-2 angiotensin II receptorType-1 angiotensin II receptorROS productionS


Description

Non classical role of vitamin D3

Please use the New WikiPathways

View approved pathways at the new wikipathways.org. This website will shutdown soon.

Quality Tags

Ontology Terms

 

Bibliography

  1. McLachlan CS; ''The angiotensin-converting enzyme 2 (ACE2) receptor in the prevention and treatment of COVID-19 are distinctly different paradigms.''; Clin Hypertens, 2020 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
136741view04:19, 20 February 2025EweitzUse gene symbols, tailor node dimensions
136740view04:03, 20 February 2025EweitzRefine node placement
136739view03:58, 20 February 2025EweitzEconomize layout
124643view12:59, 18 November 2022NhungPAdjust layout to improve readability
121511view03:29, 20 February 2022EweitzModified title
120956view10:17, 3 February 2022EgonwModified description
120955view10:14, 3 February 2022EgonwMade six pathways clickable
120233view11:29, 17 November 2021EweitzModified title
120115view14:02, 4 November 2021HumeraFiazChanges in references
120114view14:00, 4 November 2021HumeraFiazChanges in bibliography
120113view13:54, 4 November 2021HumeraFiazUpdated some graphical elements and added bibliography.
120105view15:11, 3 November 2021HumeraFiazModified description
120104view15:07, 3 November 2021HumeraFiazOntology Term : 'diabetes mellitus' added !
120103view14:51, 3 November 2021HumeraFiazModified description
120095view12:12, 2 November 2021SusanOntology Term : 'hypertension' added !
119959view10:56, 30 September 2021SusanOntology Term : 'COVID-19' added !
119958view10:55, 30 September 2021SusanOntology Term : 'vitamin D signaling pathway' added !
119957view10:55, 30 September 2021SusanOntology Term : 'vitamin D metabolic pathway' added !
119949view17:31, 28 September 2021HumeraFiazNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
1,25-dihydroxycholecalciferolMetaboliteCHEBI:17823 (ChEBI)
1-alpha- hydroxylase ProteinV9GYP0 (Uniprot-TrEMBL)
25-hydroxycholecalciferolMetaboliteCHEBI:17933 (ChEBI)
25-hydroxylaseProteinE9PS56 (Uniprot-TrEMBL)
7-DehydrocholesterolMetaboliteCHEBI:17759 (ChEBI)
ACE2ProteinQ9BYF1 (Uniprot-TrEMBL)
ACEProteinA0A0A0MSN4 (Uniprot-TrEMBL)
Angiotensin IIMetaboliteHMDB01035 (HMDB)
AngiotensinogenProteinP01019 (Uniprot-TrEMBL)
ApoptosisPathwayWP254 (WikiPathways)
CholecalciferolMetaboliteCHEBI:28940 (ChEBI)
FibrosisPathwayWP3624 (WikiPathways)
InflammationPathwayWP4479 (WikiPathways)
ROS productionPathwayWP4969 (WikiPathways)
Renal Type-1

angiotensin II

receptor		ProteinP30556 (Uniprot-TrEMBL)
ReninProteinP00797 (Uniprot-TrEMBL)
Type-1

angiotensin II

receptor		ProteinP30556 (Uniprot-TrEMBL)
Type-2

angiotensin II

receptor		ProteinP50052 (Uniprot-TrEMBL)
VasodilationPathwayWP4580 (WikiPathways)
aldosteroneMetaboliteQ184564 (Wikidata)
angiotensin IMetaboliteCHEBI:2718 (ChEBI)
cytokines and inflammationPathwayWP530 (WikiPathways)
vitamin D receptor agonistsMetaboliteCHEBI:139503 (ChEBI)

Annotated Interactions

No annotated interactions

Retrieved from "https://oldclassic.wikipathways.org/index.php/Pathway:WP5133"