miRNA role in immune response in sepsis (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Giza DE, Fuentes-Mattei E, Bullock MD, Tudor S, Goblirsch MJ, Fabbri M, Lupu F, Yeung SJ, Vasilescu C, Calin GA; ''Cellular and viral microRNAs in sepsis: mechanisms of action and clinical applications.''; Cell Death Differ, 2016 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	128743	view	04:58, 21 February 2024	Eweitz	Upgrade disease node, standardize case
	124845	view	21:01, 14 December 2022	Eweitz	Modified title
	123505	view	04:59, 29 July 2022	Egonw	Made a pathway clickable
	101725	view	21:22, 1 November 2018	Khanspers	minor update
	99016	view	21:13, 23 October 2018	Khanspers	updated interaction
	99015	view	21:02, 23 October 2018	Khanspers	Added graphic from fig 4 from the same paper, added nucleus and moved existing TNF section
	99014	view	00:00, 23 October 2018	Khanspers	improved layout
	98988	view	21:07, 19 October 2018	Khanspers	Modified title
	98402	view	05:48, 1 September 2018	Egonw	Replaced a secondary ChEBI ID with primary ID.
	98392	view	23:54, 30 August 2018	Khanspers	Ontology Term : 'nuclear factor kappa B signaling pathway' added !
	98391	view	23:54, 30 August 2018	Khanspers	Ontology Term : 'immune response pathway' added !
	98390	view	23:48, 30 August 2018	Khanspers	Modified description
	98389	view	23:46, 30 August 2018	Khanspers	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
CCL3	GeneProduct	ENSG00000277632 (Ensembl)
CCL4	GeneProduct	ENSG00000275302 (Ensembl)
CHUK	GeneProduct	ENSG00000213341 (Ensembl)
CXCL8	GeneProduct	ENSG00000169429 (Ensembl)
ELANE	GeneProduct	ENSG00000197561 (Ensembl)
GZMB	GeneProduct	ENSG00000100453 (Ensembl)
HSP70	GeneProduct
ICAM1	GeneProduct	ENSG00000090339 (Ensembl)
IKBKB	GeneProduct	ENSG00000104365 (Ensembl)
IKBKG	GeneProduct	ENSG00000269335 (Ensembl)
IL1A	GeneProduct	ENSG00000115008 (Ensembl)
IRAK1	GeneProduct	ENSG00000184216 (Ensembl)
IRAK4	GeneProduct	ENSG00000198001 (Ensembl)
IRF1	GeneProduct	ENSG00000125347 (Ensembl)
IRF5	GeneProduct	ENSG00000128604 (Ensembl)
IRF7	GeneProduct	ENSG00000185507 (Ensembl)
IkB	GeneProduct	P25963 (Uniprot-TrEMBL)	IkB Not Specified
Inflammatory Response	Pathway	WP453 (WikiPathways)
LCN2	GeneProduct	ENSG00000148346 (Ensembl)
LPS	Metabolite	CHEBI:6494 (ChEBI)
MAP3K7	GeneProduct	ENSG00000135341 (Ensembl)
MAPK14	GeneProduct	ENSG00000112062 (Ensembl)
MAPK8	GeneProduct	ENSG00000107643 (Ensembl)
MIR126	GeneProduct	ENSG00000199161 (Ensembl)
MIR146A	Rna
MIR146B	GeneProduct	ENSG00000202569 (Ensembl)
MIR149	GeneProduct	ENSG00000207611 (Ensembl)
MIR15	Rna
MIR155HG	GeneProduct	ENSG00000234883 (Ensembl)
MIR16-1	GeneProduct	ENSG00000208006 (Ensembl)
MIR16-2	GeneProduct	ENSG00000198987 (Ensembl)
MIR199A1	GeneProduct	ENSG00000207752 (Ensembl)
MIR199A2	GeneProduct	ENSG00000208024 (Ensembl)
MIR200B	GeneProduct	ENSG00000207730 (Ensembl)
MIR200C	GeneProduct	ENSG00000207713 (Ensembl)
MIR203A	GeneProduct	ENSG00000207568 (Ensembl)
MIR203B	GeneProduct	ENSG00000283165 (Ensembl)
MIR223	GeneProduct	ENSG00000274536 (Ensembl)
MIR758	GeneProduct	ENSG00000211582 (Ensembl)
MIR9-1	GeneProduct	ENSG00000207933 (Ensembl)
MIRLET7E	Rna	ENSG00000198972 (Ensembl)
MIRLET7I	GeneProduct	ENSG00000199179 (Ensembl)
MYD88	GeneProduct	ENSG00000172936 (Ensembl)
NFKB1	GeneProduct	ENSG00000109320 (Ensembl)
NFKB2	GeneProduct	ENSG00000077150 (Ensembl)
RELA	GeneProduct	5970 (Entrez Gene)
RELB	GeneProduct	5971 (Entrez Gene)
TAB1	GeneProduct	ENSG00000100324 (Ensembl)
TAB2	GeneProduct	ENSG00000055208 (Ensembl)
TLR4	GeneProduct	ENSG00000136869 (Ensembl)
TLR7	GeneProduct	ENSG00000196664 (Ensembl)
TLR8	GeneProduct	ENSG00000101916 (Ensembl)
TNF	GeneProduct	ENSG00000232810 (Ensembl)
TRAF3	GeneProduct	ENSG00000131323 (Ensembl)
TRAF6	GeneProduct	ENSG00000175104 (Ensembl)
VCAM1	GeneProduct	ENSG00000162692 (Ensembl)
c-REL	GeneProduct	5966 (Entrez Gene)
sFAS	GeneProduct
sFASL	GeneProduct

Annotated Interactions

No annotated interactions