Tgif disruption of Shh signaling (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Taniguchi K, Anderson AE, Sutherland AE, Wotton D; ''Loss of Tgif function causes holoprosencephaly by disrupting the SHH signaling pathway.''; PLoS Genet, 2012 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	117841	view	15:13, 22 May 2021	Eweitz	Modified description
	113712	view	14:06, 18 November 2020	DeSl	Removed Krzeszinski paper from GPML
	113711	view	14:04, 18 November 2020	DeSl	Removed Krzeszinski publication and info thereof, since the paper has been retracted.
	103865	view	22:02, 11 April 2019	AlexanderPico	Ontology Term : 'skeletogenic cell' added !
	103864	view	22:02, 11 April 2019	AlexanderPico	Ontology Term : 'genetic disease' added !
	103863	view	21:59, 11 April 2019	AlexanderPico	added ref
	103862	view	21:57, 11 April 2019	AlexanderPico	added mir; updated description; reorganized; red inhibitions
	88772	view	19:37, 14 August 2016	AAR&Co	Modified description
	88771	view	19:35, 14 August 2016	AAR&Co	Ontology Term : 'altered Hedgehog signaling pathway' added !
	88769	view	19:34, 14 August 2016	AAR&Co	Modified description
	87049	view	23:03, 17 July 2016	AlexanderPico	Ontology Term : 'signaling pathway' added !
	87048	view	23:01, 17 July 2016	AlexanderPico	Reduced white space
	87047	view	23:00, 17 July 2016	AlexanderPico	Periodical save, work in progress
	86152	view	10:57, 2 July 2016	Egonw	Replaced a mim-conversion with Arrow.
	86128	view	12:59, 1 July 2016	AAR&Co	Modified description
	86127	view	12:48, 1 July 2016	AAR&Co	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
FGF8	GeneProduct	ENSG00000107831 (Ensembl)
FOXG1	GeneProduct	ENSG00000176165 (Ensembl)
GLI3	GeneProduct	ENSG00000106571 (Ensembl)
NKX2-1	GeneProduct	ENSG00000136352 (Ensembl)
NODAL	GeneProduct	ENSG00000156574 (Ensembl)
SHH	GeneProduct	ENSG00000164690 (Ensembl)
SMAD2	GeneProduct	ENSG00000175387 (Ensembl)
TGIF1	GeneProduct	ENSG00000177426 (Ensembl)
TGIF2	GeneProduct	ENSG00000118707 (Ensembl)

Annotated Interactions

No annotated interactions