Leptin-insulin signaling overlap (Mus musculus)

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Description

Overlap of cellular insulin and leptin signaling

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Quality Tags

Ontology Terms

 

Bibliography

  1. Numan S, Russell DS; ''Discrete expression of insulin receptor substrate-4 mRNA in adult rat brain.''; Brain Res Mol Brain Res, 1999 PubMed Europe PMC Scholia
  2. Banks AS, Davis SM, Bates SH, Myers MG Jr; ''Activation of downstream signals by the long form of the leptin receptor.''; J Biol Chem, 2000 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
140639view06:42, 24 September 2025EgonwLonger description
139887view19:35, 9 July 2025EgonwRemoved duplicate BioPax fields
116798view10:02, 14 May 2021EweitzModified title
116796view10:01, 14 May 2021EweitzModified title
107211view14:30, 17 September 2019MaintBotChEBI identifier normalization
89977view18:44, 6 October 2016Mkutmonfix unconnected lines
72579view16:05, 23 November 2013EgonwReplace a revoked HMDB id with a ChEBI id.
71323view17:17, 17 October 2013MaintBotAutomated update of data sources
69134view18:15, 8 July 2013MaintBotUpdated to 2013 gpml schema
62835view04:55, 3 May 2013MaintBotUpdated UniProt data source
59046view20:48, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
45175view08:52, 7 October 2011ThomasOntology Term : 'leptin system pathway' added !
43785view20:58, 27 July 2011Samuel SklarSpecify description
41321view00:24, 2 March 2011MaintBotRemoved redundant pathway information and comments
39408view19:19, 23 November 2010MartijnVanIerselOntology Term : 'insulin signaling pathway' added !
32155view14:03, 14 August 2009MaintBotFixed group labels
29902view12:10, 9 June 2009Thomasupdated ensembl references
21896view11:32, 14 November 2008MaintBot[[Pathway:Mus musculus:Insulin Leptin Overlap]] moved to [[Pathway:WP578]]: Moved to stable identifier
19750view20:09, 10 October 2008MartijnVanIerselConnected lines
19748view20:07, 10 October 2008MartijnVanIerselFixed PIP2 reference
19614view13:55, 9 October 2008EveloAdded leptin backpage
19611view12:34, 9 October 2008EveloModified description
16144view08:13, 12 June 2008SusanModified categories
16142view08:12, 12 June 2008SusanModified categories
16124view12:36, 11 June 2008SusanAdding ID's
15886view12:52, 6 June 2008SusanAdding connections
15880view12:40, 6 June 2008SusanNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Akt1/PKBGeneProduct11651 (Entrez Gene)
InsrGeneProduct16337 (Entrez Gene)
InsulinGeneProduct16333 (Entrez Gene)
Irs1GeneProduct16367 (Entrez Gene)
Irs2GeneProduct384783 (Entrez Gene)
Irs3GeneProduct16369 (Entrez Gene)
Irs4GeneProduct16370 (Entrez Gene)
Jak2GeneProduct16452 (Entrez Gene)
LeprGeneProduct16847 (Entrez Gene)
LeptinGeneProductP41160 (Uniprot-TrEMBL)
P110GeneProductENSMUSG00000020573 (Ensembl)
P85GeneProductENSMUSG00000028698 (Ensembl)
PDK1GeneProduct18607 (Entrez Gene)
PIP2MetaboliteCHEBI:18348 (ChEBI)
PIP3MetaboliteCHEBI:16618 (ChEBI)
PKCGeneProductENSMUSG00000040479 (Ensembl)
Socs1GeneProduct12703 (Entrez Gene)
Socs2GeneProduct216233 (Entrez Gene)
Socs3GeneProduct12702 (Entrez Gene)
Stat3GeneProduct20848 (Entrez Gene)

Annotated Interactions

No annotated interactions

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