ALA oxylipin metabolism (Homo sapiens)

From WikiPathways

Revision as of 17:36, 31 May 2023 by Lcayer (Talk | contribs)
Jump to: navigation, search
113-HpODE13-OxoODEcytochrome P4509-HOTrE9-OxoOTrELinolenic acid15,16-DiHODE15(16)-EpODEALOX59(10)-EpODEsEH9(S)-HpOTrEALOX159,16-DiHOTrE12,13-DiHODE13-HODE9,10-DiHODE12(13)-EpODE2


Description

Alpha-linolenic acid (ALA) oxylipin metabolism by ALOX5, ALOX15, and cytochrome P450.

Please use the New WikiPathways

View approved pathways at the new wikipathways.org. This website will shutdown soon.

Quality Tags

Ontology Terms

 

Bibliography

  1. Gabbs M, Leng S, Devassy JG, Monirujjaman M, Aukema HM; ''Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs.''; Adv Nutr, 2015 PubMed Europe PMC Scholia
  2. Galliard T, Phillips DR; ''Lipoxygenase from potato tubers. Partial purification and properties of an enzyme that specifically oxygenates the 9-position of linoleic acid.''; Biochem J, 1971 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
140845view11:11, 29 October 2025EweitzClear cache
140844view11:09, 29 October 2025EweitzEconomize layout
134570view22:59, 22 July 2024EweitzModified description
126553view18:01, 31 May 2023LcayerFixed multiple incorrect changes. The root fatty acid was changed. And the 13-hydroxy metabolite metabolites were each inccorectly changed to linoleic acid metabolites
126552view17:42, 31 May 2023LcayerReverted to version '18:55, 14 April 2023' by Lcayer
126551view17:42, 31 May 2023LcayerReverted to version '19:27, 30 April 2023' by Lcayer
126550view17:36, 31 May 2023LcayerGave ALA alpha symbol
126446view19:27, 30 April 2023AlexanderPicoModified description
126445view19:26, 30 April 2023AlexanderPicoModified title
126203view18:55, 14 April 2023Khanspersupdated 13-HpODE arm
125624view20:03, 5 March 2023AlexanderPicoModified description
120082view15:31, 1 November 2021MkutmonOntology Term : 'lipid metabolic pathway' added !
120067view23:28, 25 October 2021LcayerAdded metabolite 9,16-DiHOTrE
120062view19:51, 25 October 2021Lcayerextraneous information removed
120061view19:33, 25 October 2021LcayerNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
12(13)-EpODEMetabolite16061061 (PubChem-compound)
12,13-DiHODEMetaboliteHMDB10201 (HMDB)
13-HODEMetaboliteCHEBI:137495 (ChEBI)
13-HpODEMetaboliteHMDB0003871 (HMDB)
13-OxoODEMetaboliteHMDB0004668 (HMDB)
15(16)-EpODEMetaboliteHMDB10206 (HMDB)
15,16-DiHODEMetaboliteHMDB10208 (HMDB)
9(10)-EpODEMetaboliteHMDB10220 (HMDB)
9(S)-HpOTrEMetaboliteCHEBI:60961 (ChEBI)
9,10-DiHODEMetaboliteHMDB10221 (HMDB)
9,16-DiHOTrEMetabolite
9-HOTrEMetabolite10447175 (PubChem-compound)
9-OxoOTrEMetabolite125559-74-2 (CAS)
ALOX15GeneProductENSG00000161905 (Ensembl)
ALOX5GeneProductENSG00000012779 (Ensembl)
Linolenic acidMetaboliteCHEBI:25048 (ChEBI)
cytochrome P450MetaboliteCHEBI:38559 (ChEBI)
sEHGeneProductENSG00000120915 (Ensembl)

Annotated Interactions

No annotated interactions

Retrieved from "https://oldclassic.wikipathways.org/index.php/Pathway:WP5136"
Personal tools