Sulindac metabolic pathway (Bos taurus)

Revision as of 07:04, 4 December 2025 by Khanspers (Talk | contribs)

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Description

No description

HomologyConvert: This pathway was inferred from Homo sapiens pathway WP2542(70621) with a 85.0% conversion rate.

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Brunell D, Sagher D, Kesaraju S, Brot N, Weissbach H; ''Studies on the metabolism and biological activity of the epimers of sulindac.''; Drug Metab Dispos, 2011 PubMed Europe PMC Scholia

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Revision	Action	Time	User	Comment
142123	view	07:04, 4 December 2025	Khanspers	Modified description
117617	view	11:41, 21 May 2021	Eweitz	Modified title
97757	view	13:18, 7 June 2018	Mick Eikelhof	Modified description
87598	view	08:13, 25 July 2016	MirellaKalafati	Ontology Term : 'classic metabolic pathway' added !
80713	view	15:23, 30 June 2015	Mkutmon	New pathway

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Name	Type	Database reference	Comment
CYP1A2	GeneProduct	ENSBTAG00000000085 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000140505
CYP1B1	GeneProduct	ENSBTAG00000010531 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000138061
FMO	GeneProduct
MSRA	GeneProduct	ENSBTAG00000021632 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000175806
MSRB2	GeneProduct	ENSBTAG00000044112 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000148450
MSRB3	GeneProduct	ENSBTAG00000044017 (Ensembl)	HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000174099
Sulfindac sulfide	Metabolite	4509492 (Chemspider)
Sulindac sulfone	Metabolite	4582441 (Chemspider)	The structure for the sulfone in the paper is inconsistent with the entries in ChemSpider and PubChem; I assume the paper made typographic errors.
Sulindac-R	Metabolite	16046677 (PubChem-compound)
Sulindac-S	Metabolite	11245227 (PubChem-compound)

No annotated interactions