Portal:COVID-19

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<br/><big><font color="#407F7F" size="5">Welcome to the COVID-19 Pathway Collection</font></big><br/><br/>
 
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<p>This special subset of disease pathways is being highlighted during the current COVID-19 crisis. This content is released under a CC0 waiver to be freely used, reused and distributed. Let us know if you add a new pathway or want to recommend one for this collection.</p>
 
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<p>The current list of authors and contributors of content of this portal: [[User:Fehrhart|Friederike Ehrhart]], [[User:AlexanderPico|Alex Pico]], [[User:Khanspers|Kristina Hanspers]], [[User:Amber|Amber Koning]], [[User:Rex_D_A_B|Rex D A B]], [[User:Penny|Penny Nymark]], [[User:DeSl|Denise Slenter]], [[User:C.F.Thorn|Caroline Thorn]], the Reactome project, [[User:Evelo|Chris Evelo]], [[User:L Dupuis|Lauren Dupuis]], [[User:Conroy_lipids|Matthew Conroy]], [[User:Mkutmon|Martina Kutmon]], [[User:Marvin M2|Marvin Martens]], and many more.</p>
 
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<p>We also thank the authors of all the cited articles (recursively).</p>
 
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{{#section:Help:Authors|covid-help}}
 
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|{{#imgLink:Page1-601px-COVID19-Disease-Map-project-icon.pdf.jpg|230|right|Part of the <a href="https://covid.pages.uni.lu/">COVID-19 Disease Map</a> project<p>A paper about this project was published in <a href="http://dx.doi.org/10.1038/s41597-020-0477-8">Scientific Data</a>. </p>|external|https://covid.pages.uni.lu/|COVID19 Disease Map}}
 
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== SARS-CoV-2 Pathways ==
 
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|width=100px; cell padding=50px|{{#pwImage:Pathway:WP4846|250px||SARS-CoV-2 and COVID-19 Pathway}}
 
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Collaborative project for curation of biological processes involved in the COVID-19 disease after SARS-Cov-2 infection.
 
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|width=100px|{{#pwImage:Pathway:WP4860|250px||Hijack of Ubiquitination by SARS-CoV-2}}
 
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SARS-CoV-2 includes a novel Orf10 that interacts with muliple members of the Cullin 2 ubiquitin ligase complex.
 
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|width=100px|{{#pwImage:Pathway:WP4868|250px||Type I Interferon Induction and Signaling During SARS-CoV-2 Infection}}
 
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The induction and signaling of type I interferon with specific SARS-CoV-2 protein and relevant drug.
 
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|width=100px|{{#pwImage:Pathway:WP4927|250px||COVID-19, thrombosis and anticoagulation}}
 
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|width=100px|{{#pwImage:Pathway:WP4876|250px||Activation of NLRP3 Inflammasome by SARS-CoV-2}}
 
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Orf3a from SARS-CoV has been shown to bind TRAF3 and activate the NLRP3 inflammasome.
 
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|width=100px|{{#pwImage:Pathway:WP4883|250px||SARS-CoV-2 and Angiotensin-converting enzyme 2 (ACE2) receptor : Molecular mechanisms and potential therapeutic target}}
 
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|width=100px|{{#pwImage:Pathway:WP4891|250px||COVID-19 AOP}}
 
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Experimental pathway to investigate overlap of virus-host interaction and adverse outcome pathways
 
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|width=100px|{{#pwImage:Pathway:WP4884|250px||nsp9/nsp10-mediated SARS-CoV-2 pathogenesis}}
 
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Virus-host interactome and proteomic survey of PMBCs from COVID-19 patients reveal potential virulence factors influencing SARS-CoV-2 pathogenesis
 
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|width=100px|{{#pwImage:Pathway:WP4904|250px||LDLRAD4 pathway in COVID-19}}
 
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|width=100px|{{#pwImage:Pathway:WP4936|250px||Overview of perturbations to host-cell autophagy, induced by distinct proteins of SARS-CoV-2 (Homo sapiens)}}
 
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== Other coronaviruses: MERS, SARS-CoV, etc ==
 
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|width=100px|{{#pwImage:Pathway:WP4853|250px||Coronavirus lipid metabolism}}
 
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Lipid metabolism alternations that are related to infection by the corona virus.
 
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|width=100px|{{#pwImage:Pathway:WP4863|250px||Host-pathogen interaction of human corona viruses - autophagy}}
 
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|width=100px|{{#pwImage:Pathway:WP4864|250px||Host-pathogen interaction of human corona viruses - apoptosis}}
 
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|width=100px|{{#pwImage:Pathway:WP4912|250px||SARS coronavirus and innate immunity}}
 
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|width=100px|{{#pwImage:Pathway:WP4861|250px||ER stress response in Coronavirus infection}}
 
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|width=100px|{{#pwImage:Pathway:WP4799|250px||Downregulation of ACE2 expression by SARS-CoV infection and SARS-CoV Spike protein}}
 
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|width=100px|{{#pwImage:Pathway:WP4877|250px||Host-pathogen interaction of human corona viruses - MAPK signaling}}
 
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|width=100px|{{#pwImage:Pathway:WP4880|250px||Host-pathogen interaction of human corona viruses - Interferon induction}}
 
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== More about ACE2 ==
 
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|width=100px|{{#pwImage:Pathway:WP554|250px||ACE Inhibitor Pathway}}
 
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|width=100px|{{#pwImage:Pathway:WP2729|250px||Metabolism of Angiotensinogen to Angiotensins (Reactome)}}
 
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[[Category:Portals]]
[[Category:Portals]]

Revision as of 11:18, 9 September 2020

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Welcome to the COVID-19 Pathways Portal on WikiPathways

This special subset of disease pathways is being highlighted during the current COVID-19 crisis. This content is released under a CC0 waiver to be freely used, re-used and distributed. Let us know if you add a new pathway or want to recommend one for this collection.


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Covered Pathways

Pathway Collection

All pathways tagged with "Curation: COVID-19" will be linked to this overview table, to help keep track of the relevant pathways.

Download all human COVID19 pathways

Contact us

Send questions about WikiPathways to the wikipathways-discuss mailing list.

How to add a pathway to the portal

The list of Featured Pathways is not static and can be updated at any time. If you know of a pathway that should be added, please contact the administrator.


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Contribute

We are helping to coordinate an international effort to build and curate pathway models relevant to the COVID-19 pandemic. Review the resources below to see how you can get involved.

IMPORTANT: WikiPathways is dedicated to FAIR standards. All content at WikiPathways is freely available for use and reuse by a CC0 waiver.

Curation

There are curation tests being done, that check a number of drawing patterns, e.g. as agreed with the COVID-19 Disease Maps project. The reports can be found in this repository.


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Featured Pathway

SARS coronavirus and innate immunity (Homo sapiens)

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SARS coronavirus and innate immunity
View all Featured Pathways for this Portal


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News

  • 26 Nov. 2021 A hackathon led to three new COVID-19 pathways
  • 22 Jan. 2021 An index was added to the list of curation reports
  • 28 Oct. 2020 A longer paper from the whole COVID Disease Pathways community is available on bioRxiv
  • 09 Sept. 2020 This portal was created with content from the Disease portal created in March
  • 02 Sept. 2020 COVID19 tag created and added to relevant pathways
  • 05 May 2020 The COVID-19 Disease Maps project paper was published
  • 23 March 2020 As part of the Disease portal, a collection of COVID-19 disease pathways was started


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