https://oldclassic.wikipathways.org/index.php?title=Thread:Pathway_Incorrect_%282%29&action=history Revision history for this page on the wiki en MediaWiki 1.13.1 Sat, 20 Jun 2026 16:30:56 GMT https://oldclassic.wikipathways.org/index.php?title=Thread:Pathway_Incorrect_%282%29&diff=107314&oldid=prev <p>New page: I've worked on immune and interferon signaling for years and STAT2 isn't activated by IFNg signaling. STAT2 and ISGF3 complex (STAT1:STAT2:IRF9) formation is unique to type I IFN signalin...</p> <p><b>New page</b></p><div> I've worked on immune and interferon signaling for years and STAT2 isn't activated by IFNg signaling. STAT2 and ISGF3 complex (STAT1:STAT2:IRF9) formation is unique to type I IFN signaling IFNa/b). <br /> I've looked at the paper this pathway is based on and I think they made a mistake. STAT2 can be a transcriptional target of IFNG but is never a part of the signaling cascade.<br /> I guess one of the biggest weaknesses of community derived pathway resources is that lack of evidence/provenance for each link between molecules in the signaling cascade.</div> Fri, 20 Sep 2019 09:27:03 GMT Sham.uk https://oldclassic.wikipathways.org/index.php/Thread_talk:Pathway_Incorrect_%282%29