https://oldclassic.wikipathways.org/index.php?action=history&feed=atom&title=User%3AMarvin_M2%2FAOPportal%2FIntroUser:Marvin M2/AOPportal/Intro - Revision history2026-06-20T19:53:42ZRevision history for this page on the wikiMediaWiki 1.13.1https://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91829&oldid=prevEvelo at 09:58, 31 March 20172017-03-31T09:58:43Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=== Welcome to the Adverse Outcome Pathway Portal! ===</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>=== Welcome to the Adverse Outcome Pathway Portal! ===</div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''This Adverse Outcome Pathway (AOP) portal for WikiPathways is created to highlight the molecular basis of AOPs <del class="diffchange diffchange-inline">that are relevant for the European research projects [http://www.eu-toxrisk.eu/ EU-ToxRisk] and OpenRiskNet</del>. In general, AOPs start with a Molecular Initiating Event (MIE) caused by a stressor, followed by Key Events (KEs), that lead to an Adverse Outcome (AO). These AOPs are intended specifically for regulatory <del class="diffchange diffchange-inline">decission </del>making and are stored in the AOP Knowledge Base ([http://aopkb.org/ AOPKB]). Because AOPs are simplified explanations of biological effects after the effect of a stressor<del class="diffchange diffchange-inline">, this portal </del>is created to present the molecular level of the AOPs and getting more into detail on the biological processes involved in them.'''</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>'''This Adverse Outcome Pathway (AOP) portal for WikiPathways is created to highlight the molecular basis of AOPs <ins class="diffchange diffchange-inline">or events in AOPS</ins>. <ins class="diffchange diffchange-inline"> </ins>In general, AOPs start with a Molecular Initiating Event (MIE) caused by a stressor, followed by Key Events (KEs), that lead to an Adverse Outcome (AO). These AOPs are intended specifically for regulatory <ins class="diffchange diffchange-inline">decision </ins>making and are <ins class="diffchange diffchange-inline">typically </ins>stored in the AOP Knowledge Base ([http://aopkb.org/ AOPKB]). Because AOPs are simplified explanations of biological effects after the effect of a stressor <ins class="diffchange diffchange-inline">they are not useful to describe and understand the molecular basis of the AOPs and not suited to do data analysis. Such analysis </ins>is <ins class="diffchange diffchange-inline">needed especially for in silico risk analysis that is intended to lower animal use in toxicology studies. This portal was </ins>created to present the molecular level of the AOPs and getting more into detail on the biological processes involved in them<ins class="diffchange diffchange-inline">. The development of these molecular AOPS is relevant for the European research projects on toxicology [http://www.eu-toxrisk.eu/ EU-ToxRisk] and OpenRiskNet that also fundedn part of the work</ins>. '''</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|240px|The logo of EU-ToxRisk]] <font color=#DDDDDD>space</font> [[Image:OpenRiskNet-logo.png|160px|The logo of OpenRiskNet]] <font color=#DDDDDD>space</font> [[Image:OPF-logo.png|230px|The logo of the OpenPhacts Foundation]] <font color=#DDDDDD>space</font> [[Image:ENanomapper-logo.png|180px|The logo of eNanoMapper]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|240px|The logo of EU-ToxRisk]] <font color=#DDDDDD>space</font> [[Image:OpenRiskNet-logo.png|160px|The logo of OpenRiskNet]] <font color=#DDDDDD>space</font> [[Image:OPF-logo.png|230px|The logo of the OpenPhacts Foundation]] <font color=#DDDDDD>space</font> [[Image:ENanomapper-logo.png|180px|The logo of eNanoMapper]]</div></td></tr>
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</table>Evelohttps://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91827&oldid=prevEvelo at 09:51, 31 March 20172017-03-31T09:51:04Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>=== <del class="diffchange diffchange-inline">The </del>Adverse Outcome Pathway Portal! ===</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>=== <ins class="diffchange diffchange-inline">Welcome to the </ins>Adverse Outcome Pathway Portal! ===</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''This Adverse Outcome Pathway (AOP) portal for WikiPathways is created to highlight the molecular basis of AOPs that are relevant for the European research projects [http://www.eu-toxrisk.eu/ EU-ToxRisk] and OpenRiskNet. In general, AOPs start with a Molecular Initiating Event (MIE) caused by a stressor, followed by Key Events (KEs), that lead to an Adverse Outcome (AO). These AOPs are intended specifically for regulatory decission making and are stored in the AOP Knowledge Base ([http://aopkb.org/ AOPKB]). Because AOPs are simplified explanations of biological effects after the effect of a stressor, this portal is created to present the molecular level of the AOPs and getting more into detail on the biological processes involved in them.'''</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>'''This Adverse Outcome Pathway (AOP) portal for WikiPathways is created to highlight the molecular basis of AOPs that are relevant for the European research projects [http://www.eu-toxrisk.eu/ EU-ToxRisk] and OpenRiskNet. In general, AOPs start with a Molecular Initiating Event (MIE) caused by a stressor, followed by Key Events (KEs), that lead to an Adverse Outcome (AO). These AOPs are intended specifically for regulatory decission making and are stored in the AOP Knowledge Base ([http://aopkb.org/ AOPKB]). Because AOPs are simplified explanations of biological effects after the effect of a stressor, this portal is created to present the molecular level of the AOPs and getting more into detail on the biological processes involved in them.'''</div></td></tr>
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</table>Evelohttps://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91826&oldid=prevEvelo at 09:47, 31 March 20172017-03-31T09:47:38Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>=== <del class="diffchange diffchange-inline">Welcome to the </del>Adverse Outcome Pathway <del class="diffchange diffchange-inline">portal</del>! ===</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>=== <ins class="diffchange diffchange-inline">The </ins>Adverse Outcome Pathway <ins class="diffchange diffchange-inline">Portal</ins>! ===</div></td></tr>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''This Adverse <del class="diffchange diffchange-inline">Outome </del>Pathway (AOP) portal for WikiPathways is created to highlight the molecular basis of AOPs that are relevant for the <del class="diffchange diffchange-inline">european </del>projects <del class="diffchange diffchange-inline">of </del>[http://www.eu-toxrisk.eu/ EU-ToxRisk] and OpenRiskNet. In general, AOPs start with a Molecular Initiating Event (MIE) caused by a stressor, followed by Key Events (KEs), that lead to an Adverse Outcome (AO). These AOPs are intended specifically for regulatory <del class="diffchange diffchange-inline">descision </del>making and are stored in the AOP Knowledge Base ([http://aopkb.org/ AOPKB]). Because AOPs are simplified explanations of biological effects after the effect of a stressor, this portal is created to present the molecular level of the AOPs and getting more into detail on the biological processes involved in them.'''</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>'''This Adverse <ins class="diffchange diffchange-inline">Outcome </ins>Pathway (AOP) portal for WikiPathways is created to highlight the molecular basis of AOPs that are relevant for the <ins class="diffchange diffchange-inline">European research </ins>projects [http://www.eu-toxrisk.eu/ EU-ToxRisk] and OpenRiskNet. In general, AOPs start with a Molecular Initiating Event (MIE) caused by a stressor, followed by Key Events (KEs), that lead to an Adverse Outcome (AO). These AOPs are intended specifically for regulatory <ins class="diffchange diffchange-inline">decission </ins>making and are stored in the AOP Knowledge Base ([http://aopkb.org/ AOPKB]). Because AOPs are simplified explanations of biological effects after the effect of a stressor, this portal is created to present the molecular level of the AOPs and getting more into detail on the biological processes involved in them.'''</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|240px|The logo of EU-ToxRisk]] <font color=#DDDDDD>space</font> [[Image:OpenRiskNet-logo.png|160px|The logo of OpenRiskNet]] <font color=#DDDDDD>space</font> [[Image:OPF-logo.png|230px|The logo of the OpenPhacts Foundation]] <font color=#DDDDDD>space</font> [[Image:ENanomapper-logo.png|180px|The logo of eNanoMapper]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|240px|The logo of EU-ToxRisk]] <font color=#DDDDDD>space</font> [[Image:OpenRiskNet-logo.png|160px|The logo of OpenRiskNet]] <font color=#DDDDDD>space</font> [[Image:OPF-logo.png|230px|The logo of the OpenPhacts Foundation]] <font color=#DDDDDD>space</font> [[Image:ENanomapper-logo.png|180px|The logo of eNanoMapper]]</div></td></tr>
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</table>Evelohttps://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91825&oldid=prevMarvin M2 at 07:35, 31 March 20172017-03-31T07:35:14Z<p></p>
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</table>Marvin M2https://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91823&oldid=prevMarvin M2 at 07:33, 31 March 20172017-03-31T07:33:18Z<p></p>
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</table>Marvin M2https://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91822&oldid=prevMarvin M2 at 07:32, 31 March 20172017-03-31T07:32:08Z<p></p>
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</table>Marvin M2https://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91821&oldid=prevMarvin M2 at 07:31, 31 March 20172017-03-31T07:31:37Z<p></p>
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</table>Marvin M2https://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91819&oldid=prevMarvin M2 at 07:19, 31 March 20172017-03-31T07:19:05Z<p></p>
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</table>Marvin M2https://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91798&oldid=prevMarvin M2 at 15:45, 30 March 20172017-03-30T15:45:28Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|300px|The logo of EU-ToxRisk]] : [[Image:OpenRiskNet-logo.png|<del class="diffchange diffchange-inline">300px</del>|The logo of OpenRiskNet]] : [[Image:OPF-logo.png|300px|The logo of the OpenPhacts Foundation]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|300px|The logo of EU-ToxRisk]] : [[Image:OpenRiskNet-logo.png|<ins class="diffchange diffchange-inline">200px</ins>|The logo of OpenRiskNet]] : [[Image:OPF-logo.png|300px|The logo of the OpenPhacts Foundation]]</div></td></tr>
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</table>Marvin M2https://oldclassic.wikipathways.org/index.php?title=User:Marvin_M2/AOPportal/Intro&diff=91785&oldid=prevMarvin M2 at 11:18, 30 March 20172017-03-30T11:18:44Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|300px|The logo of EU-ToxRisk]] <del class="diffchange diffchange-inline"> </del>[[Image:OpenRiskNet-logo.png|300px|The logo of OpenRiskNet]] <del class="diffchange diffchange-inline"> </del>[[Image:OPF-logo.png|300px|The logo of the OpenPhacts Foundation]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Image:Eutoxrisk-logo.jpg|300px|The logo of EU-ToxRisk]] <ins class="diffchange diffchange-inline"> : </ins>[[Image:OpenRiskNet-logo.png|300px|The logo of OpenRiskNet]] <ins class="diffchange diffchange-inline"> : </ins>[[Image:OPF-logo.png|300px|The logo of the OpenPhacts Foundation]]</div></td></tr>
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</table>Marvin M2