https://oldclassic.wikipathways.org/index.php?action=history&feed=atom&title=Thread%3ACholesterol_to_7_dehydrocholesterol_%282%29Thread:Cholesterol to 7 dehydrocholesterol (2) - Revision history2026-06-20T19:56:06ZRevision history for this page on the wikiMediaWiki 1.13.1https://oldclassic.wikipathways.org/index.php?title=Thread:Cholesterol_to_7_dehydrocholesterol_%282%29&diff=92340&oldid=prevAlexanderPico: New page: Hi SuEs. Well, the enzyme that performs the forward reaction, DHCR7, is technically capable of preforming the reverse reaction (http://enzyme.expasy.org/EC/1.3.1.21), but not under physio...2017-05-25T22:34:21Z<p>New page: Hi SuEs. Well, the enzyme that performs the forward reaction, DHCR7, is technically capable of preforming the reverse reaction (http://enzyme.expasy.org/EC/1.3.1.21), but not under physio...</p>
<p><b>New page</b></p><div>Hi SuEs. Well, the enzyme that performs the forward reaction, DHCR7, is technically capable of preforming the reverse reaction (http://enzyme.expasy.org/EC/1.3.1.21), but not under physiological conditions where [NADPH] out numbers [NADP+] by at least 100:1 (http://www.biochemj.org/content/115/4/609). There is literature on the downregulation of DHCR7 in response to high levels of cholesterol, leading to increased vitamin D production (http://www.jbc.org/content/291/16/8363.full.pdf), but I also can't find anything about biological reactions that convert cholesterol back into 7DHC. <br />
[[User:AlexanderPico|AlexanderPico]] 22:34, 25 May 2017 (UTC)</div>AlexanderPico